High-utilizing Crohn's disease patients under psychosomatic therapy

被引:15
作者
Deter H.-C. [1 ,3 ]
von Wietersheim J. [2 ,3 ]
Jantschek G. [2 ,3 ]
Burgdorf F. [1 ,3 ]
Blum B. [1 ,3 ]
Keller W. [1 ,3 ,4 ]
Feiereis H. [2 ]
Jantschek G. [2 ,3 ]
von Wietersheim J. [2 ,3 ]
Studt H.H. [1 ,4 ]
Keller W. [1 ,3 ,4 ]
Dilig R. [1 ,4 ]
Riecken E.O. [5 ]
Zeitz M. [5 ]
Vallo-Wenmes M. [5 ]
Möhring P. [6 ]
Schmelz-Schumacher E. [6 ]
Osbron W. [6 ]
Klör H.-U. [7 ]
Linn T. [7 ]
Doppl W. [7 ]
Wirsching M. [8 ]
Scheib P. [8 ]
Fritzsche K. [8 ]
Rayki O. [8 ]
Rasenack J. [9 ]
Spahmer C. [9 ]
Schölmerich J. [9 ]
Pritsch M. [10 ]
Hollzmeier S. [10 ]
机构
[1] Department of Psychosomatics and Psychotherapy, Charité Campus Benjamin Franklin, Berlin
[2] Department of Psychosomatic Medicine and Psychotherapy, Medical University Lübeck, Lübeck
[3] Medical Clinic I Gastroenterology, Charité Campus Benjamin Franklin, Berlin
[4] Department of Gastroenterology, Department of Psychosomatic Medicine, Charité Campus Benjamin Franklin, Berlin
[5] Department of Gastroenterology, Justus-Liebig University of Gießen, Gießen
[6] Department of Psychosomatics, Justus-Liebig University of Gießen, Gießen
[7] Department of Gastroenterology, Albert-Ludwigs University of Freiburg, Freiburg
[8] Department of Psychosomatics and Psychotherapy, Albert-Ludwigs University of Freiburg, Freiburg
[9] Department of Gastroenterology, Ruprecht-Karls University of Heidelberg, Heidelberg
[10] Institute of Medical Biometry and Informatic, Ruprecht-Karls University of Heidelberg, Heidelberg
关键词
Sick Leave; Health Care Utilization; Psychological Treatment; Inflammatory Bowel Disease Patient; Psychodynamic Psychotherapy;
D O I
10.1186/1751-0759-2-18
中图分类号
学科分类号
摘要
Objective: Few studies have been published on health care utilization in Crohn's disease and the influence of psychological treatment on high utilizers. Methods: The present sub study of a prospective multi centerinvestigation conducted in 87 of 488 consecutive Crohn's disease (CD) patients was designed to investigate the influence of the course of Crohn's disease on health care utilization (hospital days (HD) and sick leave days (SLD) collected by German insurance companies) and to examine the conditions of high-utilizing patients. Predictors of health care utilization should be selected. Based on a standardized somatic treatment, high health care utilizing patients of the psychotherapy and control groups should be compared before and after a one-year treatment. Results: Multivariate regression analysis identified disease activity at randomization as an important predictor of the clinical course (r2 = 0.28, p < 0.01). Health care utilization correlated with duration of disease (p < 0.04), but the model was not significant (r2 = 0.15, p = 0.09). The patients' level of anxiety, depression and lack of control at randomization predicted their health-related quality of life at the end of the study (r2 = 0.51, p < 0.00001). Interestingly, steroid intake and depression (t1) predicted the combined outcome measure (clinical course, HRQL, health care utilization) of Crohn's disease at the end of the study (r2 = 0.22, p < 0.001). Among high utilizers, a significantly greater drop in HD (p < 0.03) and in mean in SLD were found in the treatment compared to the control group. Conclusion: The course of Crohn's disease is influenced by psychological as well as somatic factors; especially depression seems important here. A significant drop of health care utilization demonstrates the benefit of psychological treatment in the subgroup of high-utilizing CD patients. Further studies are needed to replicate the findings of the clinical outcome in this CD subgroup. © 2008 Deter et al; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 41 条
  • [1] Katon W., Korff Mv., Liu F., Bush T., Russo J., Lipscomb P., Wagner E., A randomised trial of psychiatric consultation with distressed high utlilizas, Gen Hospital Psychiatry, 14, pp. 86-98, (1992)
  • [2] Verhoefs M., Sutherland L., Outpatient health care utilization of patients with inflammatory bowel disease, Dig Dis, 11, pp. 1124-1128, (1995)
  • [3] Hay A.R., Hay J.W., Inflammatory bowel disease: Cost of-illness, J Clin Gastroenterol, 14, pp. 309-317, (1992)
  • [4] Drossman D.A., Patrick D.L., Mitchell C.M., Zagami E.A., Appelbaum M.I., Health-related quality of life in inflammatory bowel disease- functional status and patient worries and concerns, Dig Dis Sc, 34, pp. 1379-1386, (1989)
  • [5] Helzer J.E., Chammas S., Norland C.C., Stillings W.A., Alpers D.H., A study of the association between Crohn's disease and psychiatric Illness, Gastroenterology, 86, 2, pp. 324-330, (1984)
  • [6] Andrews H., Barczak P., Allan R.N., Psychiatric illness in patients with inflammatory bowel disease, Gut, 28, pp. 1600-1604, (1987)
  • [7] Deter H.C., Rapf M., Gladisch R., Rohner R., Psychodiagnostische Verlaufsuntersuchungen von Morbus-Crohn-Patienten während der internistischen Intensivbehandlung, Z Gastroenterol, 31, pp. 703-710, (1993)
  • [8] Fullwood A., Drossman D.A., The relationship of psychiatric Illness with gastrointestinal disease, Annu Rev Med, 46, pp. 483-496, (1995)
  • [9] Levenstein S., Li Z., Almer S., Barbosa A., Marquis P., Moser G., Sperber A., Toner B., Drossman D.A., Cross-cultural variation in disease-related concerns among patients with inflammatory bowel disease, Am J Gastroenterol, 96, pp. 1822-1830, (2001)
  • [10] Janke K.H., Klump B., Gregor M., Meisner C., Haeuser W., Determinants of life satisfaction in inflammatory bowel disease, Inflamm Bowel Dis, 11, pp. 272-286, (2005)