1H, 13C, and 15N NMR assignments of a Drosophila Hedgehog autoprocessing domain

被引：0
作者：
Jian Xie
Zhenming Du
Brian Callahan
Marlene Belfort
Chunyu Wang
机构：
[1] Rensselaer Polytechnic Institute,Biochemistry and Biophysics Graduate Program, Center for Biotechnology and Interdisciplinary Studies
[2] State University of New York at Binghamton,Department of Chemistry
[3] University at Albany,Department of Biological Sciences
来源：
Biomolecular NMR Assignments | 2014年 / 8卷
关键词：
Assignments; Autoprocessing; Hedgehog; NMR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [13C, 15N]-labeled and [2H, 13C, 15N])-labeled proteins.
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页码：279 / 281
页数：2
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