Glutathione S-transferase activity in the liver of mice with different sensitivity to hepatocarcinogenic effects ofo-aminoazotoluene

被引：0
作者：
L. Yu. Zakharova
L. F. Gulyaeva
O. V. Narkhova
V. I. Kaledin
机构：
[1] Siberian Division of the Russian Academy of Medical Sciences,Institute of Molecular Biology and Biophysics
[2] Siberian Division of the Russian Academy of Sciences,Institute of Cytology and Genetics
来源：
Bulletin of Experimental Biology and Medicine | 2000年 / 129卷
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摘要：
Glutathione S-transferase activity was detected in the liver of inbred mice sensitive (CBA) and resistant (CC57BR and C57B1) to hepatocarcinogenic effects ofo-aminoazotoluene. High liver glutathione S-transferase activity was found in CC57BR and C57B1 and low in CBA mice treated with this carcinogen. Thus, interstrain differences in glutathione S-transferase activity probably determine the resistance too-aminoazotoluene-induced hepatocarcinogenesis.
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页码：149 / 150
页数：1
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