Glutathione S-transferase activity in the liver of mice with different sensitivity to hepatocarcinogenic effects ofo-aminoazotoluene

被引：0

作者：

L. Yu. Zakharova

L. F. Gulyaeva

O. V. Narkhova

V. I. Kaledin

机构：

[1] Siberian Division of the Russian Academy of Medical Sciences,Institute of Molecular Biology and Biophysics

[2] Siberian Division of the Russian Academy of Sciences,Institute of Cytology and Genetics

来源：

Bulletin of Experimental Biology and Medicine | 2000年 / 129卷

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摘要：

Glutathione S-transferase activity was detected in the liver of inbred mice sensitive (CBA) and resistant (CC57BR and C57B1) to hepatocarcinogenic effects ofo-aminoazotoluene. High liver glutathione S-transferase activity was found in CC57BR and C57B1 and low in CBA mice treated with this carcinogen. Thus, interstrain differences in glutathione S-transferase activity probably determine the resistance too-aminoazotoluene-induced hepatocarcinogenesis.

引用

页码：149 / 150

页数：1

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