The CIOMS view on the use of placebo in clinical trials

被引：0
作者：
Juhana E. Idänpään-Heikkilä
Sev Fluss
机构：
[1] c/o World Health Organization,Council for International Organizations of Medical Sciences (CIOMS)
来源：
Science and Engineering Ethics | 2004年 / 10卷
关键词：
Placebo; Ethics of placebo; Clinical trials and placebo; Choice of control; Research guidelines; Research ethics; Comparator;
D O I：
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学科分类号：
摘要：
Based on worldwide consultations with experts in science and ethics the revised CIOMS 2002 International Ethical Guidelines for Biomedical Research Involving Human Subjects provide guidance on when the use of placebo as a comparator in clinical research is ethically acceptable. The article reviews the main points of the CIOMS Guidelines and commentaries including the use of placebo in situations where the best current method is available and the relation of placebo to established effective intervention. It discusses the use of placebo in externally sponsored research in low-resource countries and requirements for informed consent related to placebo studies.
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页码：23 / 28
页数：5
相关论文
共 3 条
  • [1] Temple R.(2000)Placebo-controlled trials and active control trials in the evaluation of new treatments. Part 1: Ethical and scientific issues Ann Int Med 133 455-463
  • [2] Ellenberg S.S.(2001)Ethical principles for the guidance of physicians in medical research- the Declaration of Helsinki Bull WHO 79 279-279
  • [3] Idänpään-Heikkilä JE(undefined)undefined undefined undefined undefined-undefined
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