Ligand Binding Assays in the 21st Century Laboratory: Automation

被引:0
作者
Ago B. Ahene
Chris Morrow
David Rusnak
Susan Spitz
Joel Usansky
Holger Pils
Francesca Civoli
Kinnari Pandya
Brian Sue
Daniel Leach
John Derent
机构
[1] XOMA Corporation,
[2] Genentech,undefined
[3] BioAgilytix Labs,undefined
[4] MedImmune,undefined
[5] LLC,undefined
[6] Thermo Fisher,undefined
[7] Hamilton Company,undefined
[8] Amgen,undefined
[9] Tecan,undefined
[10] Janssen Research Development,undefined
[11] LLC,undefined
来源
The AAPS Journal | 2012年 / 14卷
关键词
laboratory automation; ligand binding assay; plug and play; assay dynamics; liquid handling; ELISA;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:142 / 153
页数:11
相关论文
共 36 条
[1]  
DeSilva B(2003)Recommendations for the bioanalytical method validation of ligand-binding assays to support pharmacokinetic assessments of macromolecules Pharm Res 20 1885-1900
[2]  
Smith W(2010)Strategies to minimize variability and bias associated with manual pipetting in ligand binding assays to assure data quality of protein therapeutic quantification J Pharm Biomed Anal 53 623-630
[3]  
Weiner R(2009)Application of multi-factorial design of experiments to successfully optimize immunoassays for robust measurements of therapeutic proteins J Pharm Biomed Anal 49 311-318
[4]  
Kelley M(2008)Optimizing ELISAs for precision and robustness using laboratory automation and statistical design of experiments J Immunol Methods 337 35-41
[5]  
Smolec J(1996)Application of experimental design techniques to optimize a competitive ELISA J Immunol Methods 190 151-161
[6]  
Lee B(2003)An ultra HTS process for the identification of small molecule modulators of orphan G protein-coupled receptors Drug Discov Today 8 785-792
[7]  
Pandya K(2005)Considerations when implementing automated methods into GxP laboratories JALA 10 182-191
[8]  
Ray C(undefined)undefined undefined undefined undefined-undefined
[9]  
Brunner L(undefined)undefined undefined undefined undefined-undefined
[10]  
Wang J(undefined)undefined undefined undefined undefined-undefined