Advancement of wound care from grafts to bioengineered smart skin substitutes

被引:98
作者
Augustine R. [1 ]
Kalarikkal N. [1 ,2 ]
Thomas S. [1 ,3 ]
机构
[1] International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Priyadarshini Hills, Kottayam, 686-560, Kerala
[2] School of Pure and Applied Physics, Mahatma Gandhi University, Priyadarshini Hills, Kottayam, 686-560, Kerala
[3] School of Chemical Sciences, Mahatma Gandhi University, Priyadarshini Hills, Kottayam, 686-560, Kerala
关键词
Angiogenesis; Skin grafts; Skin substitutes; Smart biomaterials; Wound healing;
D O I
10.1007/s40204-014-0030-y
中图分类号
学科分类号
摘要
This review gives a brief description on the skin and its essential functions, damages or injury which are common to the skin and the role of skin substitute to replace the functions of the skin soon after an injury. Skin substitutes have crucial role in the management of deep dermal and full thickness wounds. At present, there is no skin substitute in the market that can replace all the functions of skin ‘and the research is still continuing for a better alternative. This review is an attempt to recollect and report the past efforts including skin grafting and recent trends like use of bioengineered smart skin substitutes in wound care. Incorporation functional moieties like antimicrobials and wound healing agents are also described. © The Author(s) 2014.
引用
收藏
页码:103 / 113
页数:10
相关论文
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