Nickel-Catalyzed Reductive Couplings

被引：0
作者：
Xuan Wang
Yijing Dai
Hegui Gong
机构：
[1] Shanghai University,Department of Chemistry, Center for Supramolecular Materials and Catalysis
[2] Tongji University,Shanghai Key Lab of Chemical Assessment and Sustainability
来源：
Topics in Current Chemistry | 2016年 / 374卷
关键词：
Reductive coupling; Nickel catalysis; Electrophiles; Selectivity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The Ni-catalyzed reductive coupling of alkyl/aryl with other electrophiles has evolved to be an important protocol for the construction of C–C bonds. This chapter first emphasizes the recent progress on the Ni-catalyzed alkylation, arylation/vinylation, and acylation of alkyl electrophiles. A brief overview of CO2 fixation is also addressed. The chemoselectivity between the electrophiles and the reactivity of the alkyl substrates will be detailed on the basis of different Ni-catalyzed conditions and mechanistic perspective. The asymmetric formation of C(sp3)–C(sp2) bonds arising from activated alkyl halides is next depicted followed by allylic carbonylation. Finally, the coupling of aryl halides with other C(sp2)–electrophiles is detailed at the end of this chapter.
引用
收藏
相关论文
共 384 条
  • [1] Gu J(2015)undefined Org Chem Front 2 1411-9763
  • [2] Wang X(2014)undefined J Org Chem 79 4793-326
  • [3] Xue W(2014)undefined Chem Eur J 20 6828-undefined
  • [4] Gong H(2015)undefined Acc Chem Res 48 1767-undefined
  • [5] Everson DA(2014)undefined Chem Eur J 20 8242-undefined
  • [6] Weix DJ(1997)undefined Top Curr Chem 185 141-undefined
  • [7] Knappke CE(2011)undefined Chem Rev 111 1417-undefined
  • [8] Grupe S(2010)undefined Nat Chem 2 125-undefined
  • [9] Gärtner D(2008)undefined Acc Chem Res 41 1555-undefined
  • [10] Corpet M(2004)undefined Adv Synth Catal 346 1525-undefined
12345678910