Condensation of thiourea with uracyl derivatives containing ketone and ketoester fragments, alkylation and macrocyclization of the condensation products

被引:0
作者
E. S. Krylova
V. E. Semenov
V. D. Akamsin
V. S. Reznik
机构
[1] Russian Academy of Sciences,Arbuzov Institute of Organic and Physical Chemistry, Kazan Research Center
来源
Russian Journal of General Chemistry | 2010年 / 80卷
关键词
Thiourea; General Chemistry; Anhydrous Ethanol; Compound Versus; Pyrimidine Ring;
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学科分类号
摘要
By condensation of thiourea with 6-methyluracyl derivatives containing ketone and ketoester fragmenst in the alkyl chains attached to the nitrogen atoms of the pyrimidine ring the products containing 6-methyl- or 3,6-dimethyluracyl fragment and one or two 6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyrimidin-5-yl fragments were synthesized. These compounds can be alkylated with alkyl bromides.
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页码:1364 / 1368
页数:4
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