Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands

被引:0
作者
Fabrizio Fierro
Lior Peri
Harald Hübner
Alina Tabor-Schkade
Lukas Waterloo
Stefan Löber
Tara Pfeiffer
Dorothee Weikert
Tamir Dingjan
Eitan Margulis
Peter Gmeiner
Masha Y Niv
机构
[1] The Hebrew University of Jerusalem,The Institute of Biochemistry, Food Science and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment
[2] Friedrich-Alexander-Universität Erlangen-Nürnberg,Department of Chemistry and Pharmacy, Medicinal Chemistry
来源
Cellular and Molecular Life Sciences | 2023年 / 80卷
关键词
TAS2R; GPCR; Bitterness inhibitors; Structure-based drug design; Taste;
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