Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms

被引：0
|
作者：
Ameneh Jafari
Fahima Danesh Pouya
Zahra Niknam
Meghdad Abdollahpour‑Alitappeh
Mostafa Rezaei-Tavirani
Yousef Rasmi
机构：
[1] Motamed Cancer Institute,Advanced Therapy Medicinal Product (ATMP) Department, Breast Cancer Research Center
[2] ACECR,Proteomics Research Center, School of Allied Medical Sciences
[3] Shahid Beheshti University of Medical Sciences,Department of Biochemistry, School of Medicine
[4] Urmia University of Medical Sciences,Cellular and Molecular Biology Research Center
[5] Larestan University of Medical Sciences,Student Research Committee
[6] Larestan University of Medical Sciences,Cellular and Molecular Research Center
[7] Urmia University of Medical Sciences,undefined
来源：
Molecular Biology Reports | 2022年 / 49卷
关键词：
SARS-CoV-2; COVID -19 vaccine platform; Vaccine candidate; Vaccine efficacy; Nanoparticles-based vaccine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The world is grappling with an unprecedented public health crisis COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates and socioeconomic impacts of the COVID-19, its control is crucial. In the absence of specific treatment, vaccines represent the most efficient way to control and stop the pandemic. Many companies around the world are currently making efforts to develop the vaccine to combat COVID-19. This review outlines key strategies for generating SARS-CoV-2 vaccine candidates, along with the mechanism of action, advantages, and potential limitations of each vaccine. The use of nanomaterials and nanotechnology for COVID-19 vaccines development will also be discussed.
引用
收藏
页码：4943 / 4957
页数：14
相关论文
共 15 条
  • [1] Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
    Jafari, Ameneh
    Danesh Pouya, Fahima
    Niknam, Zahra
    Abdollahpour-Alitappeh, Meghdad
    Rezaei-Tavirani, Mostafa
    Rasmi, Yousef
    MOLECULAR BIOLOGY REPORTS, 2022, 49 (06) : 4943 - 4957
  • [2] Challenges and prospects of COVID-19 vaccine development based on the progress made in SARS and MERS vaccine development
    Begum, Jubeda
    Mir, Nasir Akbar
    Dev, Kapil
    Buyamayum, Bidyarani
    Wani, Mohd Yaqoob
    Raza, Meesam
    TRANSBOUNDARY AND EMERGING DISEASES, 2021, 68 (03) : 1111 - 1124
  • [3] Host factors and vaccine efficacy: Implications for COVID-19 vaccines
    Falahi, Shahab
    Kenarkoohi, Azra
    JOURNAL OF MEDICAL VIROLOGY, 2022, 94 (04) : 1330 - 1335
  • [4] Genetic diversity of the Pneumococcal CbpA: Implications for next-generation vaccine development
    Abry, Muna F.
    Kimenyi, Kelvin M.
    Osowo, Fred O.
    Odhiambo, Willingtone O.
    Sewe, Steven O.
    Kulohoma, Benard W.
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2015, 11 (05) : 1261 - 1267
  • [5] Review of Current Vaccine Development Strategies to Prevent Coronavirus Disease 2019 (COVID-19)
    Bennet, Bindu M.
    Wolf, Jayanthi
    Laureano, Rodrigo
    Sellers, Rani S.
    TOXICOLOGIC PATHOLOGY, 2020, 48 (07) : 800 - 809
  • [6] Considerations on the clinical development of COVID-19 vaccine from trial design perspectives
    Jiang, Zhiwei
    Wang, Xuanyi
    Xia, Jielai
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2021, 17 (03) : 656 - 660
  • [7] From Conspiracy to Hesitancy: The Longitudinal Impact of COVID-19 Vaccine Conspiracy Theories on Perceived Vaccine Effectiveness
    Salazar-Fernandez, Camila
    Baeza-Rivera, Maria Jose
    Manriquez-Robles, Diego
    Salinas-Onate, Natalia
    Sallam, Malik
    VACCINES, 2023, 11 (07)
  • [8] How the case counting window affected vaccine efficacy calculations in randomized trials of COVID-19 vaccines
    Doshi, Peter
    Fung, Kaiser
    JOURNAL OF EVALUATION IN CLINICAL PRACTICE, 2024, 30 (01) : 105 - 106
  • [9] Vaccine versus Variants (3Vs): Are the COVID-19 Vaccines Effective against the Variants? A Systematic Review
    Hayawi, Kadhim
    Shahriar, Sakib
    Serhani, Mohamed Adel
    Alashwal, Hany
    Masud, Mohammad M.
    VACCINES, 2021, 9 (11)
  • [10] Vaccine Effects on Susceptibility and Symptomatology Can Change the Optimal Allocation of COVID-19 Vaccines: South Korea as an Example
    Choi, Wongyeong
    Shim, Eunha
    JOURNAL OF CLINICAL MEDICINE, 2021, 10 (13)
12