A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

[1] Agnandji ST(2011)First results of phase 3 trial of RTS, S/AS01 malaria vaccine in African children N Engl J Med 365 1863-1875

[2] Lell B(2012)A phase 3 trial of RTS, S/AS01 malaria vaccine in African infants N Engl J Med 367 2284-2295

[3] Soulanoudjingar SS(2013)Immune mechanisms in malaria: new insights in vaccine development Nat Med 19 168-178

[4] Fernandes JF(2013)Efficacy of RTS, S malaria vaccines: individual-participant pooled analysis of phase 2 data Lancet Infect Dis 13 319-327

[5] Abossolo BP(2014)Estimates of the changing age-burden of P. falciparum malaria disease in sub-Saharan Africa Nat Commun 5 3136-2532

[6] Conzelmann C(2008)Efficacy of RTS, S/AS01E vaccine against malaria in children 5 to 17 months of age N Engl J Med 359 2521-1420

[7] Methogo BG(2004)Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial Lancet 364 1411-749

[8] Doucka Y(2011)Safety and efficacy of the RTS, S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial Lancet Infect Dis 11 741-2544

[9] Flamen A(2009)A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS, S malaria vaccine candidates in children in Gabon Plos One 4 e7611-1934

[10] Mordmueller B(2009)Randomized controlled trial of RTS, S/AS02(D) and RTS, S/AS01(E) malaria candidate vaccines given according to different schedules in Ghanaian children Plos One 4 7302-336

[1] Agnandji ST(2011)First results of phase 3 trial of RTS, S/AS01 malaria vaccine in African children N Engl J Med 365 1863-1875

[2] Lell B(2012)A phase 3 trial of RTS, S/AS01 malaria vaccine in African infants N Engl J Med 367 2284-2295

[3] Soulanoudjingar SS(2013)Immune mechanisms in malaria: new insights in vaccine development Nat Med 19 168-178

[4] Fernandes JF(2013)Efficacy of RTS, S malaria vaccines: individual-participant pooled analysis of phase 2 data Lancet Infect Dis 13 319-327

[5] Abossolo BP(2014)Estimates of the changing age-burden of P. falciparum malaria disease in sub-Saharan Africa Nat Commun 5 3136-2532

[6] Conzelmann C(2008)Efficacy of RTS, S/AS01E vaccine against malaria in children 5 to 17 months of age N Engl J Med 359 2521-1420

[7] Methogo BG(2004)Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial Lancet 364 1411-749

[8] Doucka Y(2011)Safety and efficacy of the RTS, S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial Lancet Infect Dis 11 741-2544

[9] Flamen A(2009)A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS, S malaria vaccine candidates in children in Gabon Plos One 4 e7611-1934

[10] Mordmueller B(2009)Randomized controlled trial of RTS, S/AS02(D) and RTS, S/AS01(E) malaria candidate vaccines given according to different schedules in Ghanaian children Plos One 4 7302-336