Patient-derived tumour xenografts as models for oncology drug development

被引:0
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作者
John J. Tentler
Aik Choon Tan
Colin D. Weekes
Antonio Jimeno
Stephen Leong
Todd M. Pitts
John J. Arcaroli
Wells A. Messersmith
S. Gail Eckhardt
机构
[1] School of Medicine,Division of Medical Oncology, Department of Medicine
[2] University of Colorado,undefined
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摘要
In this Review, Tentler et al. present the opportunities and challenges of using patient-derived tumour xenograft models in oncology drug development, provide specific disease examples, and describe concepts regarding predictive biomarker development and future applications.
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页码:338 / 350
页数:12
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