The efficacy of a low-dose, monodisperse parasympathicolytic aerosol compared with a standard aerosol from a metered-dose inhaler

被引:0
作者
P. Zanen
L. T. Go
J.-W. J. Lammers
机构
[1] Department of Pulmonary Diseases,
[2] University Hospital Utrecht,undefined
[3] PO Box 85500,undefined
[4] NL-3508 GA,undefined
[5] Utrecht,undefined
[6] The Netherlands Tel. + 31 30 2506150; Fax: +31 30 2542155,undefined
来源
European Journal of Clinical Pharmacology | 1998年 / 54卷
关键词
Key words Aerosols; Ipratropium bromide;
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摘要
Objective: In previous experiments we showed that monodisperse bronchodilator aerosols with a median mass aerodynamic diameter of 2.8 μm induced stronger bronchodilatations than larger aerosols and that the dilatations were clinically relevant at low doses. To discover whether the bronchodilator effects of these low-dose monodisperse aerosols differed from those of standard dosages delivered by metered-dose inhalers, we carried out a comparative trial.
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页码:27 / 30
页数:3
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