Doppler ultrasound assessment of the splanchnic circulation in preterms with neonatal sepsis at risk for necrotizing enterocolitis

被引:31
作者
Hashem R.H. [2 ]
Mansi Y.A. [1 ]
Almasah N.S. [1 ]
Abdelghaffar S. [1 ]
机构
[1] Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo
[2] Department of Radiology, Faculty of Medicine, Cairo University, Cairo
关键词
Doppler ultrasonography; NEC; Preterms; Sepsis; Splanchnic circulation;
D O I
10.1007/s40477-016-0228-z
中图分类号
学科分类号
摘要
Objective: To evaluate the role of Doppler ultrasonography in the assessment of splanchnic circulation’s hemodynamic changes in septic preterms at risk of necrotizing enterocolitis. Methods: A total of 51 septic preterms were divided into two groups: 25 preterms with clinical signs of necrotizing enterocolitis (NEC) and 26 preterms with no clinical signs of NEC. Both groups were assessed with Doppler ultrasonography of the celiac and superior mesenteric arteries, and each septic preterm’s peak systolic velocity (PSV), end-diastolic velocity (EDV), resistivity index (RI), and pulsatility index (PI) was calculated and recorded. Results: These included a statistically significant lower PSV (p: 0.001) and a lower EDV (p: 0.001) in the superior mesenteric artery in the septic group with clinical signs of NEC in comparison with the septic group with no clinical signs of NEC. A statistically significant (p < 0.001) higher PSV celiac (CA)/PSV superior mesenteric (SMA) ratio was found for the group of septic preterms with clinical signs of NEC when compared to the other group. Conclusion: The study results showed that Doppler ultrasonography of the splanchnic circulation can be a tool for the early identification of NEC cases among septic preterms. © 2017, Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB).
引用
收藏
页码:59 / 67
页数:8
相关论文
共 27 条
[1]  
Stoll B.J., Epidemiology of necrotizing enterocolitis, Clin Perinatol, 21, pp. 205-218, (1994)
[2]  
Luedtke S.A., Yang J.T., Wild H.E., Probiotics and necrotizing enterocolitis: finding the missing pieces of the probiotic puzzle, J Pediatr Pharmacol Ther, 17, 4, pp. 308-328, (2012)
[3]  
Moss R.L., Kalish L.A., Duggan C., Et al., Clinical parameters do not adequately predict outcome in necrotizing enterocolitis: a multi-institutional study, J Perinatol, 28, 10, pp. 665-674, (2008)
[4]  
Lin P.W., Nasr T.R., Stoll B.J., Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention, Semin Perinatol, 32, 2, pp. 70-82, (2008)
[5]  
Kempley S.T., Murdoch E., Splanchnic hemodynamic disturbances in neonatal sepsis, Arch Dis Child Fetal Neonatal, 83, pp. F139-F142, (2000)
[6]  
Grosfeld J.L., Chaet M., Molinari F., Et al., Increased risk of necrotizing Enterocolitis in premature infants with patent ductus arteriosus treated with indomethacin, Ann Surg, 224, 3, pp. 350-355, (1996)
[7]  
Kim W.Y., Kim W.S., Kim I.O., Et al., Sonographic evaluation of neonates with early-stage necrotizing enterocolitis, Pediatr Radiol, 35, 11, pp. 1056-1061, (2005)
[8]  
Faingold R., Daneman A., Tomlinson G., Et al., Necrotizing Enterocolitis: Assessment of Bowel Viability with Color Doppler US, Radiology, 235, 2, pp. 587-594, (2005)
[9]  
Silva C.T., Daneman A., Navarro O.M., Et al., Correlation of sonographic findings and outcome in necrotizing enterocolitis, Pediatr Radiol, 37, 3, pp. 274-282, (2007)
[10]  
Miranda F.C., Sameshima Y.T., Deutsch A.D.A., Et al., Ultrasonography in diagnosis of necrotizing enterocolitis, Einstein, 7, 1, pp. 91-95, (2009)