Theories of the pathogenesis of inclusion body myositis

被引：35
作者：
Greenberg S.A. [1 ]
机构：
[1] Department of Neurology, Division of Neuromuscular Disease, Harvard Medical School, Boston, MA 02115
来源：
Current Rheumatology Reports | 2010年 / 12卷 / 3期
基金：
美国国家卫生研究院;
关键词：
Inclusion body myositis;
D O I：
10.1007/s11926-010-0102-5
中图分类号：
学科分类号：
摘要：
Inclusion body myositis is a progressive disease of the skeletal muscle. Here, specific theories of its pathogenesis are reviewed and general considerations pertaining to modeling of this disease discussed. Understanding of inclusion body myositis disease mechanism remains extremely poor. Current published animal models do not represent the disease. Future studies need to consider the critical role of biomarkers and methodologic issues in their discovery. © Springer Science+Business Media, LLC 2010.
引用
收藏
页码：221 / 228
页数：7
相关论文
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