Chemical biology of abscisic acid

被引：0
作者：
Nobutaka Kitahata
Tadao Asami
机构：
[1] The University of Tokyo,Department of Applied Biological Chemistry
[2] RIKEN,Plant Chemical Biology Unit
来源：
Journal of Plant Research | 2011年 / 124卷
关键词：
Abscisic acid (ABA); Chemical biology; Inhibitor; Probe;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Chemical biology is a discipline that utilizes chemicals to elucidate biological mechanisms and physiological functions. Various abscisic acid (ABA) derivatives have revealed the structural requirement for the perception by ABA receptors while biotin or caged derivatives of ABA have disclosed the localization of several ABA-binding proteins. Recently, selective ABA agonist has been used to identify ABA receptors. Furthermore, ABA biosynthesis and catabolic inhibitors have contributed to the identification of new ABA functions in plant growth and development. The physiological function of ABA in non-plant organisms has gradually been revealed. In this review, we discuss the development of small bioactive chemicals and their significance in ABA research.
引用
收藏
页码：549 / 557
页数：8
相关论文
共 402 条
  • [1] Allan AC(1994)Two transduction pathways mediate rapid effects of abscisic acid in Plant Cell 6 1319-1328
  • [2] Fricker MD(2006) guard cells Bioorg Med Chem Lett 16 3302-3305
  • [3] Ward JL(2003)A new-azole inhibitor of ABA 8′-hydroxylase: effect of the hydroxyl group substituted for geminal methyl groups in the six-membered ring Plant Physiol 133 448-455
  • [4] Beale MH(2009)Chemical genetic approaches to plant biology Bioorg Med Chem 17 2902-2912
  • [5] Trewavas AJ(2007)Sesquiterpene-like inhibitors of a 9- Proc Natl Acad Sci USA 104 5759-5764
  • [6] Araki Y(1992)-epoxycarotenoid dioxygenase regulating abscisic acid biosynthesis in higher plants Plant Physiol 99 1258-1260
  • [7] Miyawaki A(2000)Abscisic acid is an endogeous cytokine in human granulocytes with cyclic ADP-ribose as second messenger Biochem 39 13614-13624
  • [8] Miyashita T(2010)Involvement of a lipoxygenase-like enzyme in abscisic acid biosynthesis Annu Rev Plant Biol 61 651-679
  • [9] Mizutani M(1986)Inhibitors of absicsic acid 8′-hydroxylase Physiol Plant 67 472-476
  • [10] Hirai N(2002)Abscisic acid: emergence of a core signal network Plant Cell 14 S15-S45
12345678910