5-Formylcytosine alters the structure of the DNA double helix

被引：0
|
作者：
Eun-Ang Raiber
Pierre Murat
Dimitri Y Chirgadze
Dario Beraldi
Ben F Luisi
Shankar Balasubramanian
机构：
[1] University of Cambridge,Department of Chemistry
[2] University of Cambridge,Department of Biochemistry
[3] Cancer Research UK Cambridge Institute,undefined
[4] Li Ka Shing Centre,undefined
[5] School of Clinical Medicine,undefined
[6] University of Cambridge,undefined
来源：
Nature Structural & Molecular Biology | 2015年 / 22卷
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摘要：
5-Formylcytosine (5fC) is implicated in active DNA demethylation and has been proposed to act as an epigenetic signal. Balasubramanian and colleagues now report that this base modification imparts a unique, previously undescribed conformation to DNA.
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页码：44 / 49
页数：5
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