Impact of Lactic Acid and Genipin Concentration on Physicochemical and Mechanical Properties of Chitosan Membranes

被引:0
作者
Izabela Kondratowicz
Ibrahim Shalayel
Małgorzata Nadolska
Seiya Tsujimura
Yoshifumi Yamagata
Isao Shitanda
Abdelkader Zebda
机构
[1] Univ. Grenoble Alpes,Advanced Materials Center
[2] TIMC-IMAG/CNRS/INSERM,Division of Material Science, Faculty of Pure and Applied Science
[3] UMR 5525,Department of Pure and Applied Chemistry, Faculty of Science and Technology
[4] Gdańsk University of Technology,Japanese
[5] University of Tsukuba,French lAboratory for Semiconductor physics and Technology (J
[6] Anton Paar Japan K. K,F AST)
[7] Tokyo University of Science,undefined
[8] 2641,undefined
[9] CNRS–Université Grenoble Alpes–Grenoble,undefined
[10] INP–University of Tsukuba,undefined
[11] 1-1-1 Tennodai,undefined
来源
Journal of Polymers and the Environment | 2023年 / 31卷
关键词
Chitosan Membranes; Genipin; Crosslinking; Lactic Acid; Physicochemical Properties; Mechanical Properties;
D O I
暂无
中图分类号
学科分类号
摘要
Chitosan is a linear polysaccharide that has a growing interest in several biomedical applications. Due to its poor solubility in water, aqueous organic acids are required to dissolve chitosan. Chitosan-based materials have been widely investigated for several industrial and biomedical applications. It becomes crucial to study the effect of the additives on the chemical, physical, and mechanical properties of chitosan. Here, we present the effect of various material combinations: chitosan, lactic acid and genipin. We intend to study the effect of elevated concentrations of lactic acid on the stability and elasticity of chitosan membranes. Our research also presents the effect of the concentration of genipin crosslinker, a biocompatible natural product, on the properties of chitosan materials. Obtained results show that lactic acid acts as a physical and a chemical crosslinker between chitosan chains, which leads to increase chitosan membrane stretchability thanks to the plasticizing characteristic of lactic acid. Obtained membranes show a high solubility in water that can be avoided by the introduction of genipin as a crosslinker. This significantly reduces the solubility of membranes in aqueous solutions and makes them more stable even under low pH’s.
引用
收藏
页码:1221 / 1231
页数:10
相关论文
共 128 条
[1]  
Zebda A(2018)Challenges for successful implantation of biofuel cells Bioelectrochemistry 124 57-72
[2]  
Alcaraz J-P(1999)Properties of the poly(vinyl alcohol)/chitosan blend and its effect on the culture of fibroblast in vitro Biomaterials 20 1479-1487
[3]  
Vadgama P(2018)Cosmetics and cosmeceutical applications of chitin, Chitosan and their derivatives Polym (Basel) 10 213-110
[4]  
Chuang W-Y(2008)Characterization of poly(vinyl alcohol)/Chitosan Hydrogels as vascular tissue Engineering Scaffolds Macromol Symp 269 106-1846
[5]  
Young T-H(2015)Stability of Chitosan—A Challenge for Pharmaceutical and Biomedical Applications Mar Drugs 13 1819-142
[6]  
Yao C-H(2005)Effect of organic and inorganic acids on concentrated chitosan solutions and gels Int J Biol Macromol 37 134-703
[7]  
Chiu W-Y(2020)Chitosan Films in Food Applications. Tuning Film Properties by changing acidic dissolution conditions Polym (Basel) 13 1-1738
[8]  
Aranaz I(2019)Impact of acid type for chitosan dissolution on the characteristics and biodegradability of cornstarch/chitosan based films Int J Biol Macromol 138 693-2602
[9]  
Acosta N(2020)Effects of lactic acid and mixed acid aqueous solutions on the preparation, structure and properties of thermoplastic chitosan Eur Polym J 134 109850-1172
[10]  
Civera C(2003)Thermal and mechanical properties of plasticized poly(L-lactic acid) J Appl Polym Sci 90 1731-356