Pharmacological evaluation of benzimidazole derivatives with potential antiviral and antitumor activity

被引：0
作者：
Sherifa M. Abu-Bakr
Fatma A. Bassyouni
Mohamed Abdel Rehim
机构：
[1] National Research Centre,Department of Chemistry of Natural and Microbial Products
[2] National Research Centre,Department of Chemistry of Natural and Microbial Products and Pharmaceutical Research, Center of Excellence for Advanced Sciences
[3] Stockholm University,Department of Analytical Chemistry
来源：
Research on Chemical Intermediates | 2012年 / 38卷
关键词：
Benzimidazole derivatives; Combinatorial synthesis; Microwave-assisted synthesis; Heterocycles; Topoisomerase inhibitors; Protein kinase inhibitor; Antitumor; Antiviral;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In recent years the synthesis of benzimidazole and its derivatives has attracted the attention of many organic chemists because of the compounds’ interesting biological activity and the crucial importance of the benzimidazole unit in the function of these biologically important molecules. Benzimidazole-based polyheterocyclic compounds have several interesting biological properties. Simple synthetic strategies leading to benzimidazole-based fused polyheterocyclic systems and the antiviral and anticancer biological activity of the compounds are surveyed in this review article.
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页码：2523 / 2545
页数：22
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