The Predicted Long-Term Benefits of Ensuring Timely Treatment and Medication Adherence in Early Schizophrenia

被引：0
作者：
Marcela Horvitz-Lennon
Zachary Predmore
Patrick Orr
Mark Hanson
Richard Hillestad
Mike Durkin
Antoine C. El Khoury
Soeren Mattke
机构：
[1] RAND Corporation,
[2] RAND Corporation,undefined
[3] Johns Hopkins University,undefined
[4] University of Southern California,undefined
[5] Information Mapping,undefined
[6] Janssen Scientific Affairs,undefined
[7] LLC,undefined
来源：
Administration and Policy in Mental Health and Mental Health Services Research | 2020年 / 47卷
关键词：
Schizophrenia; Treatment adherence; Early detection; Simulation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The impact of initiatives aimed at reducing time in untreated psychosis during early-stage schizophrenia will be unknown for many years. Thus, we simulate the effect of earlier treatment entry and better antipsychotic drug adherence on schizophrenia-related hospitalizations, receipt of disability benefits, competitive employment, and independent/family living over a ten-year horizon. We predict that earlier treatment entry reduces hospitalizations by 12.6–14.4% and benefit receipt by 7.0–8.5%, while increasing independent/family living by 41.5–46% and employment by 42–58%. We predict larger gains if a pro-adherence intervention is also used. Our findings suggest substantial benefits of timely and consistent early schizophrenia care.
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页码：357 / 365
页数：8
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