A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit

被引：142

作者：

Wai-Man Tang

Enoch Chan

Ching-Yee Kwok

Yee-Ki Lee

Jian-Hong Wu

Chun-Wai Wan

Robbie Yat-Kan Chan

Peter Hoi-Fu Yu

Shun-Wan Chan

机构：

[1] Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hong Kong SAR

[2] Division of Science and Technology, Programme of Food Science and Technology, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai

[3] State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong SAR

来源：

Inflammopharmacology | 2012年 / 20卷 / 6期

关键词：

Anticancer; Immunomodulation; Lycium barbarum fruit; Pharmacology; Polysaccharides; Traditional Chinese medicine;

D O I：

10.1007/s10787-011-0107-3

中图分类号：

学科分类号：

摘要：

The anticancer effects of traditional Chinese medicine (TCM) have attracted the attention of the public vis-a-vis existing cancer therapies with various side effects. Lycium barbarum fruit, commonly known as Gou Qi Zi in China, is a potential anticancer agent/adjuvant. Its major active ingredients, L. barbarum polysaccharides (LBP), scopoletin and 2-O-b-D-glucopyranosyl-L-ascorbic acid (AA-2bG), are found to have apoptotic and antiproliferative effects on cancer cell lines. Moreover, LBP also contributes to body's immunomodulatory effects and enhances effects of other cancer therapies. It is not known whether there are any undesirable effects. Further studies on its pharmacological mechanisms and toxicology could facilitate a safe usage of this TCM herb. © 2011 Springer Basel AG.

引用

页码：307 / 314

页数：7

共 70 条

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