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Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Ctr, Biotechnol Res Inst, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Ctr, Biotechnol Res Inst, Kowloon, Hong Kong, Peoples R China