Synthesis, crystal and molecular structure of 2-(3-chloropropyl)-6-methyl- 4-phenylquinazoline 3-oxide

被引：0

作者：

Kulikov O.V. ^{[1
]}

Mazepa A.V. ^{[1
]}

机构：

[1] A. B. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine

来源：

Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 7期

关键词：

Mass spectrometry; Quinazoline; X-ray diffraction structural analysis;

D O I：

10.1007/s10593-007-0139-1

中图分类号：

学科分类号：

摘要：

The acylation of the syn isomer of the oxime of 2-amino-5- methylbenzophenone with 4-chlorobutyryl chloride gives a mixture of the anti isomer of the 4-chlorobutyryloximine of 2-(4-chlorobutyryl)amino-5- methylbenzophenone and 2-(3-chloropropyl)-6-methyl-4-phenylquinazoline 3-oxide. The crystal and molecular structure of this oxide was established by X-ray diffraction structural analysis. The molecule is planar. The electron impact fragmentation of 2-(3-chloropropyl)-6-methyl-4-phenylquinazoline 3-oxide was discussed. © 2007 Springer Science+Business Media, Inc.

引用

页码：879 / 886

页数：7

共 32 条

[1] Molecular and crystal structures of 6-substituted 4-phenylquinazoline 3-oxides and 2,2,6-trimethyl-4-phenyl-1,2-dihydroquinazoline
O. V. Kulikov
I. G. Filippova
M. Gdaniec
V. I. Pavlovskii
Yu. A. Simonov
Journal of Structural Chemistry, 2006, 47 : 339 - 345
[2] Molecular and crystal structures of 6-substituted 4-phenylquinazoline 3-oxides and 2,2,6-trimethyl-4-phenyl-1,2-dihydroquinazoline
Kulikov, O. V.
Filippova, I. G.
Gdaniec, M.
Pavlovskii, V. I.
Simonov, Yu. A.
JOURNAL OF STRUCTURAL CHEMISTRY, 2006, 47 (02) : 339 - 345
[3] Synthesis and crystal structure of 4-(2-chlorophenylamino)-6-methoxy-2-phenylquinazoline
Z.-Y. Xing
Q. Zhao
Y. Fu
F. Ye
Chemistry of Heterocyclic Compounds, 2011, 47 : 607 - 610
[4] SYNTHESIS AND CRYSTAL STRUCTURE OF 4-(2-CHLOROPHENYLAMINO)-6-METHOXY-2-PHENYLQUINAZOLINE
Xing, Z. -Y.
Zhao, Q.
Fu, Y.
Ye, F.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2011, 47 (05) : 607 - 610
[5] Synthesis and alkylation of piperidinium 4,5-trans-3-cyano-6-hydroxy-4-(2-iodophenyl)-6-methyl-5-(2-methyl phenyl)-carbamoyl-1,4,5,6-tetrahydropyridine-2-thiolate. Molecular and crystal structure of 3-(2-iodophenyl)-2-(4-phenyl-2-thiazolyl)acrylonitrile
Krivokolysko S.G.
Dyachenko V.D.
Nesterov V.N.
Litvinov V.P.
Chemistry of Heterocyclic Compounds, 2001, 37 (7) : 855 - 860
[6] Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates
Fathalla, Walid
Pazdera, Pavel
ARKIVOC, 2007, : 236 - 243
[7] Molecular and crystal structure of 5-benzoyl-3-cyano-2-ethylthio-6-trifluoromethylpyridine
Yakunin Ya.Yu.
Dyachenko V.D.
Rusanov E.B.
Litvinov V.P.
Chemistry of Heterocyclic Compounds, 2001, Kluwer Academic/Plenum Publishers (37) : 202 - 205
[8] Structural and electronic properties of 3-[2-(3, 4-dimethoxy phenyl)-ethyl]-2-methyl-3H-quinazoline-4-one: experimental (X-ray crystal structure) and theoretical (quantum chemical calculations) approach
Gandhi, Sahaj A.
Modh, Rajeshkumar D.
Patel, Urmila H.
Patel, Bharatkumar D.
Chikhalia, Kishor H.
Patel, Amit C.
MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 2020, 708 (01) : 98 - 120
[9] Organotin esterification of (E)-3-(3-fluoro-phenyl)-2-(4-chlorophenyl)-2-propenoic acid:: synthesis, spectroscopic characterization and in vitro biological activities.: Crystal structure of [Ph3Sn(OC(O)C(4-ClC6H4)= CH(3-FC6H4))]
Sadiq-ur-Rehman
Shahid, K
Ali, S
Bhatti, MH
Parvez, M
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2005, 690 (05) : 1396 - 1408
[10] Studies on quinazoline chemistry. 4. Unexpected route of acylation of alkyl 2-(4,4-diphenyl-1,2,3,4-tetrahydro-2-quinazolinylidene)acetates. Molecular structure of methyl 2-(4,4-diphenyl)-1,2,3,4-tetrahydro-2-quinazolinylidene)-3- oxobutanoate
Gromachevskaya E.V.
Kaigorodova E.A.
Zavodnik V.E.
Krapivin G.D.
Chemistry of Heterocyclic Compounds, 2007, 43 (06) : 748 - 754

← 1 2 3 4 →