Youth with severe mental illness and complex non-somatic motor abnormalities: conflicting conceptualizations and unequal treatment

被引：3

作者：

Peter Andersson

Lee E. Wachtel

Johan Lundberg

Esmail Jamshidi

Johan Bring

Mathias Rask-Andersen

Håkan Jarbin

Jussi Jokinen

Adrian E. Desai Boström

机构：

[1] Department of Clinical Neuroscience/Psychology, Karolinska Institute, Stockholm

[2] Centre for Clinical Research Dalarna, Uppsala University, Falun

[3] Kennedy Krieger Institute, Johns Hopkins School of Medicine, Baltimore, MD

[4] Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm

[5] Stockholm Health Care Services, Region Stockholm, Stockholm

[6] Department of Clinical Sciences/Psychiatry, Umeå University, Umeå

[7] Statisticon AB, Uppsala

[8] Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala

[9] Department of Clinical Sciences Lund, Section of Child and Adolescent Psychiatry, Lund University, Lund

[10] Child and Adolescent Psychiatry, Region Halland, Halmstad

[11] Department of Women’s and Children’s Health/Neuropediatrics, Karolinska Institutet, Stockholm

来源：

npj Mental Health Research | / 1卷 / 1期

关键词：

D O I：

10.1038/s44184-022-00013-8

中图分类号：

学科分类号：

摘要：

Two emerging diagnostic concepts promote distinct treatments for youth with acute-onset motor abnormalities and severe concurrent psychiatric symptoms: Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric catatonia. Both have institutional approval in parts of Europe and in the USA, meriting an unconditional comparison of supporting evidence. Here we report results of qualitative and quantitative analyses of literature and Swedish National Registry Data suggesting that (1) catatonic patients are liable to fulfilling diagnostic criteria for PANS, (2) three conservatively assessed PANS case-reports present with possible unrecognized catatonia, (3) lithium and electroconvulsive therapy usage frequencies in Swedish minors (exclusively recommended for severe mental illness) are strongly intercorrelated and unequally distributed across Swedish counties, (4) established severe mental disorders are rarely overtly considered amongst PANS-specific research and (5) best-available evidence treatments appear markedly superior for pediatric catatonia compared to PANS in both childhood and adolescence. Prioritizing treatments for pediatric catatonia in concerned subjects could markedly improve treatment outcomes. © The Author(s) 2022.

引用

共 58 条

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