Synthesis and anti-inflammatory activity of N-arylamides of 4-aryl- and 4-(thiophen-2-yl)-2-[2-(furan-2-carbonyl)hydrazono]-4-oxobutanoic acids

被引:0
|
作者
S. N. Igidov
A. Yu. Turyshev
S. V. Chashchina
D. A. Shipilovskikh
I. N. Chernov
O. V. Zvereva
P. S. Silaichev
N. M. Igidov
S. A. Shipilovskikh
机构
[1] Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation,Scientific Research Institute of Chemistry
[2] Merck LLC,School of Physics and Engineering
[3] Perm State National Research University,undefined
[4] Perm National Research Polytechnic University,undefined
[5] Lobachevsky State University of Nizhny Novgorod,undefined
[6] ITMO University,undefined
来源
Russian Chemical Bulletin | 2023年 / 72卷
关键词
2,4-dioxobutanoic acids; 3-hydrazonofuran-2(3; )-ones; anti-inflammatory activity;
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学科分类号
摘要
N-Arylamides of 4-aryl/4-(thiophen-2-yl)-2-[2-(furan-2-carbonyl)hydrazono]-4-oxobutanoic acids were synthesized by the reaction of N′-(5-aryl/5-(thiophen-2-yl)-2-oxofuran-3(2H)-ylidene)furan-2-carbohydrazides with arylamines and evaluated for antiinflammatory activity.
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页码:2241 / 2248
页数:7
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