Clinical and endoscopic features of angiosarcoma of the colon: Two case reports and a review of the literature

被引：11
作者：
Sherid M. [1 ]
Sifuentes H. [2 ]
Brasky J. [3 ,4 ]
Shah D.A. [3 ]
Ehrenpreis E.D. [3 ]
机构：
[1] Saint Francis Hospital, 355 Ridge Avenue, Evanston
[2] Section of Gastroenterology and Hepatology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA
[3] NorthShore University HealthSystem, 777 Park Avenue West, Highland Park
[4] Lifetract Clinical Research Fellow, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston
来源：
Journal of Gastrointestinal Cancer | 2013年 / 44卷 / 1期
关键词：
Angiosarcoma; CD117; CD31; CD34; Clinical features; Colon; Colonoscopy; Gastrointestinal tract; Hemangiosarcoma; Immunohistochemistry; Rectum; Sarcoma;
D O I：
10.1007/s12029-012-9431-0
中图分类号：
学科分类号：
摘要：
Background: Angiosarcoma of the gastrointestinal tract is an extremely rare tumor. We present two cases of angiosarcoma of the colon. One patient developed syncope and anemia and the other had rectal bleeding. Discussion: Endoscopic findings of the colon were different; the first case demonstrated a reddened colonic fold without an obvious mass and the other had an ulcerated friable mass. Both of the tumors had positive immunohistochemical stains for CD31 and CD34 (one was also positive for CD117). Surgery was not performed in either case. Treatment included chemotherapy with imatinib for the first patient and paclitaxel for the second. Prognosis for this tumor is generally poor; in our cases, one patient was still alive after 5 months of follow-up and the other died within 2 months of diagnosis. After presenting our cases, we reviewed the current literature on angiosarcoma of the colon. © 2012 Springer Science+Business Media, LLC.
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页码：12 / 21
页数：9
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