A lung adenocarcinoma patient with co-mutations of MET and EGFR exon20 insertion responded to crizotinib

被引:0
作者
Yan Chen
Bo Jiang
Yuange He
Chu Zhang
Wenjie Zhou
Cheng Fang
Dejian Gu
Minxia Zhang
Mei Ji
Juntao Shi
Xin Yang
机构
[1] The Third Affiliated Hospital of Soochow University,Department of Oncology
[2] The First People’s Hospital of Changzhou,Department of Thoracic Surgery
[3] The Third Affiliated Hospital of Soochow University,Geneplus
[4] The First People’s Hospital of Changzhou,Beijing, 9th Floor
[5] No.6 Building,Department of Cardiothoracic Surgery
[6] Peking University Medical Industrial Park,undefined
[7] The Third Affiliated Hospital of Soochow University,undefined
[8] The First People’s Hospital of Changzhou,undefined
来源
BMC Medical Genomics | / 15卷
关键词
NCSLC; mutation; mutation; Double mutation; Crizotinib;
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  • [1] Doroshow DB(2018)Treatment of advanced non-small cell lung cancer in 2018 JAMA Oncol 4 569-570
  • [2] Herbst RS(2018)Immune checkpoint inhibitors in cancer therapy: a focus on T-regulatory cells Immunol Cell Biol 96 21-33
  • [3] Sasidharan Nair V(2019)Mechanisms regulating PD-L1 expression on tumor and immune cells J Immunother Cancer 7 305-454
  • [4] Elkord E(2018)The biology and management of non-small cell lung cancer Nature 553 446-1019
  • [5] Chen S(2012)Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study Lancet Oncol 13 1011-1991
  • [6] Crabill GA(2019)Crizotinib in c-MET- or ROS1-positive NSCLC: results of the AcSe phase II trial Ann Oncol 30 1985-1064
  • [7] Pritchard TS(2017)Coexistence of MET exon 14 mutations with EGFR mutations in non-small cell lung cancer J Clin Oncol 35 e20636-486
  • [8] McMiller TL(2019)The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer J Immunother Cancer 7 98-229
  • [9] Wei P(2019)Prevalence of recurrent oncogenic fusion in mismatch repair-deficient colorectal carcinoma with hypermethylated MLH1 and wild-type BRAF and KRAS Modern Pathol 32 1053-730
  • [10] Pardoll DM(2016)MET exon 14 skipping in non-small cell lung cancer Oncologist 21 481-849