The effect of Psoroptes ovis infestation on ovine epidermal barrier function

被引：0
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作者：
Miriam R Stoeckli
Tom N McNeilly
David Frew
Edward J Marr
Alasdair J Nisbet
Adri HM van den Broek
Stewart TG Burgess
机构：
[1] Moredun Research Institute,The Royal (Dick) School of Veterinary Studies
[2] The University of Edinburgh,Hospital for Small Animals, Easter Bush Veterinary Centre, Division of Veterinary Clinical Sciences
[3] The Roslin Institute,undefined
[4] The University of Edinburgh,undefined
来源：
Veterinary Research | / 44卷
关键词：
Atopic Dermatitis; Stratum Corneum; House Dust Mite; Epidermal Barrier; Skin Barrier Function;
D O I：
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学科分类号：
摘要：
Sheep scab is an intensively pruritic, exudative and allergic dermatitis of sheep caused by the ectoparasitic mite Psoroptes ovis. The purpose of the present study was to investigate the effect of P. ovis infestation on different components of the ovine epidermal barrier within the first 24 hours post-infestation (hpi). To achieve this, the expression of epidermal differentiation complex (EDC) genes and epidermal barrier proteins, the nature and severity of epidermal pathology and transepidermal water loss (TEWL) were evaluated.
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