Benefits and Challenges of Rare Genetic Variation in Alzheimer’s Disease

被引:0
|
作者
Detelina Grozeva
Salha Saad
Georgina E. Menzies
Rebecca Sims
机构
[1] Cardiff University,Division of Psychological Medicine and Clinical Neuroscience, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine
[2] Cardiff University,UK Dementia Research Institute at Cardiff, School of Medicine
来源
Current Genetic Medicine Reports | 2019年 / 7卷
关键词
Alzheimer’s disease; Genetics; Susceptibility; Rare variants;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:53 / 62
页数:9
相关论文
共 50 条
  • [41] Insight into the genetic etiology of Alzheimer's disease: A comprehensive review of the role of rare variants
    Hoogmartens, Julie
    Cacace, Rita
    Van Broeckhoven, Christine
    ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING, 2021, 13 (01)
  • [42] The landscape of rare genetic variation associated with inflammatory bowel disease and Parkinson's disease comorbidity
    Kars, Meltem Ece
    Wu, Yiming
    Stenson, Peter D.
    Cooper, David N.
    Burisch, Johan
    Peter, Inga
    Itan, Yuval
    GENOME MEDICINE, 2024, 16 (01):
  • [43] A Blood Test for Alzheimer's Disease: Progress, Challenges, and Recommendations
    Kiddle, Steven J.
    Voyle, Nicola
    Dobson, Richard J. B.
    JOURNAL OF ALZHEIMERS DISEASE, 2018, 64 : S289 - S297
  • [44] Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer’s disease risk
    Gloriia Novikova
    Shea J. Andrews
    Alan E. Renton
    Edoardo Marcora
    Molecular Neurodegeneration, 16
  • [45] Alzheimer's disease genetics: current knowledge and future challenges
    Hollingworth, Paul
    Harold, Denise
    Jones, Lesley
    Owen, Michael J.
    Williams, Julie
    INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2011, 26 (08) : 793 - 802
  • [46] Familial Alzheimer's disease: Genetic influences on the disease process (Review)
    Lippa, CF
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 1999, 4 (05) : 529 - 536
  • [47] NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge
    Greenfest-Allen, Emily
    Valladares, Otto
    Kuksa, Pavel P.
    Gangadharan, Prabhakaran
    Lee, Wan-Ping
    Cifello, Jeffrey
    Katanic, Zivadin
    Kuzma, Amanda B.
    Wheeler, Nicholas
    Bush, William S.
    Leung, Yuk Yee
    Schellenberg, Gerard
    Stoeckert, Christian J., Jr.
    Wang, Li-San
    ALZHEIMERS & DEMENTIA, 2024, 20 (02) : 1123 - 1136
  • [48] Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease
    Inkster, Becky
    Rao, Anil W.
    Ridler, Khanum
    Filippini, Nicola
    Whitcher, Brandon
    Nichols, Thomas E.
    Wetten, Sally
    Gibson, Rachel A.
    Borrie, Michael
    Kertesz, Andrew
    Guzman, Danilo A.
    Loy-English, Inge
    Williams, Julie
    Saemann, Philipp G.
    Auer, Dorothee P.
    Holsboer, Florian
    Tozzi, Federica
    Muglia, Pierandrea
    Merlo-Pich, Emilio
    Matthews, Paul M.
    NEUROBIOLOGY OF AGING, 2012, 33 (03) : 457 - 465
  • [49] Rare Genetic Variants of the Transthyretin Gene Are Associated with Alzheimer’s Disease in Han Chinese
    Qun Xiang
    Rui Bi
    Min Xu
    Deng-Feng Zhang
    Liwen Tan
    Chen Zhang
    Yiru Fang
    Yong-Gang Yao
    Molecular Neurobiology, 2017, 54 : 5192 - 5200
  • [50] Genetic insights into immune mechanisms of Alzheimer's and Parkinson's disease
    Nott, Alexi
    Holtman, Inge R.
    FRONTIERS IN IMMUNOLOGY, 2023, 14