Benefits and Challenges of Rare Genetic Variation in Alzheimer’s Disease

被引：0
|
作者：
Detelina Grozeva
Salha Saad
Georgina E. Menzies
Rebecca Sims
机构：
[1] Cardiff University,Division of Psychological Medicine and Clinical Neuroscience, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine
[2] Cardiff University,UK Dementia Research Institute at Cardiff, School of Medicine
来源：
Current Genetic Medicine Reports | 2019年 / 7卷
关键词：
Alzheimer’s disease; Genetics; Susceptibility; Rare variants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：53 / 62
页数：9
相关论文
共 50 条
  • [31] Apolipoprotein E genetic variation and Alzheimer's disease - A meta-analysis
    Rubinsztein, DC
    Easton, DF
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 1999, 10 (03) : 199 - 209
  • [32] Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease
    Zahratka, Jeffrey A.
    Shao, Yvonne
    Shaw, McKenzie
    Todd, Kaitlin
    Formica, Shane V.
    Khrestian, Maria
    Montine, Thomas
    Leverenz, James B.
    Bekris, Lynn M.
    NEUROBIOLOGY OF AGING, 2017, 51 : 43 - 53
  • [33] Challenges and hopes for Alzheimer's disease
    Tatulian, Suren A.
    DRUG DISCOVERY TODAY, 2022, 27 (04) : 1027 - 1043
  • [34] Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease
    Gaare, Johannes J.
    Nido, Gonzalo S.
    Sztromwasser, Pawel
    Knappskog, Per M.
    Dahl, Olav
    Lund-Johansen, Morten
    Maple-Grodem, Jodi
    Alves, Guido
    Tysnes, Ole-Bjorn
    Johansson, Stefan
    Haugarvoll, Kristoffer
    Tzoulis, Charalampos
    MOVEMENT DISORDERS, 2018, 33 (10) : 1591 - 1600
  • [35] Alzheimer's disease: the benefits of early treatment
    Gauthier, SG
    EUROPEAN JOURNAL OF NEUROLOGY, 2005, 12 : 11 - 16
  • [36] Contribution of TARDBP to Alzheimer's Disease Genetic Etiology
    Brouwers, Nathalie
    Bettens, Karolien
    Gijselinck, Ilse
    Engelborghs, Sebastiaan
    Pickut, Barbara A.
    Van Miegroet, Helen
    Montoya, Ana Gil
    Mattheijssens, Maria
    Peeters, Karin
    De Deyn, Peter P.
    Cruts, Marc
    Sleegers, Kristel
    Van Broeckhoven, Christine
    JOURNAL OF ALZHEIMERS DISEASE, 2010, 21 (02) : 423 - 430
  • [37] What is a genetic cause? The example of Alzheimer's Disease
    Dekkers W.
    Rikkert M.O.
    Medicine, Health Care and Philosophy, 2006, 9 (3) : 273 - 284
  • [38] Singular cases of Alzheimer's disease disclose new and old genetic "acquaintances"
    Coppola, Cinzia
    Saracino, Dario
    Oliva, Mariano
    Cipriano, Lorenzo
    Puoti, Gianfranco
    Pappata, Sabina
    Di Fede, Giuseppe
    Catania, Marcella
    Ricci, Martina
    Cimini, Sara
    Giaccone, Giorgio
    Bonavita, Simona
    Rossi, Giacomina
    NEUROLOGICAL SCIENCES, 2021, 42 (05) : 2021 - 2029
  • [39] Genetic study of Sardinian patients with Alzheimer's disease
    Piscopo, P
    Manfredi, A
    Malvezzi-Campeggi, L
    Crestini, A
    Spadoni, O
    Cherchi, R
    Deiana, E
    Piras, MR
    Confaloni, A
    NEUROSCIENCE LETTERS, 2006, 398 (1-2) : 124 - 128
  • [40] Genetic risk factors in familial Alzheimer's disease
    Sorbi, S
    Forleo, P
    Tedde, A
    Cellini, E
    Ciantelli, M
    Bagnoli, S
    Nacmias, B
    MECHANISMS OF AGEING AND DEVELOPMENT, 2001, 122 (16) : 1951 - 1960
12345