Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

被引:0
作者
Laura J Blair
Haley D Frauen
Bo Zhang
Bryce A Nordhues
Sara Bijan
Yen-Chi Lin
Frank Zamudio
Lidice D Hernandez
Jonathan J Sabbagh
Maj-Linda B Selenica
Chad A Dickey
机构
[1] University of South Florida,Department of Molecular Medicine
[2] Byrd Alzheimer’s Institute,Department of Pharmaceutical Science
[3] James A. Haley Veteran’s Hospital,undefined
[4] University of South Florida,undefined
[5] Byrd Alzheimer’s Institute,undefined
来源
Acta Neuropathologica Communications | / 3卷
关键词
rTg4510; Alzheimer’s disease; Blood-brain barrier; Tau; Vascular;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 617 条
  • [21] Brayne C(2009)Human truncated tau is using a different mechanism from amyloid-beta to damage the blood-brain barrier J Alzheimers Dis 18 897-481
  • [22] Savva GM(2009)Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy Am J Pathol 174 228-1607
  • [23] Garwood C(2005)Tau suppression in a neurodegenerative mouse model improves memory function Science 309 476-4169
  • [24] Drew D(2006)Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy Am J Pathol 168 1598-263
  • [25] Shaw PJ(2013)Accelerated neurodegeneration through chaperone-mediated oligomerization of tau J Clin Invest 123 4158-S96
  • [26] Ince PG(2013)Characteristics of TBS-extractable hyperphosphorylated tau species: aggregation intermediates in rTg4510 mouse brain J Alzheimers Dis 33 249-989
  • [27] Bowman GL(2014)Tau oligomers as potential targets for early diagnosis of tauopathy J Alzheimers Dis 40 S91-1341
  • [28] Kaye JA(2010)Acute canine distemper encephalitis is associated with rapid neuronal loss and local immune activation J Gen Virol 91 980-119
  • [29] Moore M(2008)Opening of the blood-brain barrier during isoflurane anaesthesia Eur J Neurosci 28 1330-15382
  • [30] Waichunas D(1997)Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat J Comp Neurol 388 106-153