Is there a role for glycated albumin in the diagnosis of gestational diabetes mellitus?

被引:0
作者
Fernando Chimela Chume
Paula Breitenbach Renz
Mayana Kieling Hernandez
Priscila Aparecida Correa Freitas
Joíza Lins Camargo
机构
[1] Universidade Federal do Rio Grande do Sul Porto Alegre,Graduate Program in Medical Sciences: Endocrinology
[2] Universidade Zambeze,Faculty of Health Sciences
[3] Hospital de Clínicas de Porto Alegre (HCPA),Laboratory Diagnosis Division, Clinical Biochemistry Unit
[4] Hospital de Clínicas de Porto Alegre,Endocrinology Division and Experimental Research Centre
[5] Hospital de Clínicas de Porto Alegre,Diabetes and Metabolism Group, Centro de Pesquisa Clínica
来源
Endocrine | 2021年 / 72卷
关键词
Gestational diabetes mellitus; Glycated albumin; HbA1c; Oral glucose tolerance test; Diagnostic accuracy;
D O I
暂无
中图分类号
学科分类号
摘要
Previously studies in general population reported that glycated albumin (GA) presents similar accuracy as HbA1c for detecting diabetes.The present study showed that in pregnant women the area under the curve (AUC) for GA in the diagnosis of gestational diabetes mellitus (GDM) was much lower than AUC for HbA1c.Unlike HbA1c, GA does not have the ability to correctly discriminate those with and without GDM.Our findings may provide a cautious approach when assessing glycaemic status using GA in pregnant women, since pregnancy can be considered a confounding factor.
引用
收藏
页码:681 / 687
页数:6
相关论文
共 137 条
  • [1] Poolsup N(2020)Diagnosis and classification of diabetes mellitus Diabetes Care 43 S13-S28
  • [2] Suksomboon N(2014)Effect of treatment of gestational diabetes mellitus: a systematic review and meta-analysis PLOS ONE 9 c1395-129
  • [3] Amin M(2010)Effects of treatment in women with gestational diabetes mellitus: systematic review and meta-analysis BMJ 340 123-2002
  • [4] Horvath K(2013)Benefits and harms of treating gestational diabetes mellitus: a systematic review and meta-analysis for the U.S. Preventive Services Task Force and the National Institutes of Health Office of Medical Applications of Research Ann. Intern. Med. 159 1991-682
  • [5] Koch K(2008)Hyperglycemia and adverse pregnancy outcomes N. Engl. J. Med. 358 676-31
  • [6] Jeitler K(2010)International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy Diabetes Care 33 1-1449
  • [7] Matyas E(2013)NIH consensus development conference: diagnosing gestational diabetes mellitus NIH Consens. State Sci. Statements 29 1435-304
  • [8] Bender R(2019)Diagnostic accuracy of glycated hemoglobin for gestational diabetes mellitus: a systematic review and meta-analysis Clin. Chem. Lab. Med. 57 296-288
  • [9] Bastian H(2017)Glycated albumin: a potential biomarker in diabetes Arch. Endocrinol. Metab. 61 279-277
  • [10] Hartling L(2014)Fructosamine and glycated albumin for risk stratification and prediction of incident diabetes and microvascular complications: a prospective cohort analysis of the Atherosclerosis Risk in Communities (ARIC) study Lancet Diabetes Endocrinol. 2 269-3036