Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome by protecting against glycocalyx damage and suppressing inflammatory signaling pathways

被引:0
作者
Dong Zhang
Bo-yang Qi
Wei- wei Zhu
Xiao Huang
Xiao-zhi Wang
机构
[1] Affiliated Hospital of Binzhou Medical University,Department of Respirator Medicine and Intensive Care Unit
来源
Inflammation Research | 2020年 / 69卷
关键词
Crocin; Inflammatory responses; Glycocalyx damage; LPS; ARDS;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:267 / 278
页数:11
相关论文
共 210 条
  • [1] Lin X(2016)β1-Na(+), K(+)-ATPase gene therapy upregulates tight junctions to rescue lipopolysaccharide-induced acute lung injury Gene Ther 23 489-499
  • [2] Barravecchia M(2015)3,5,4'-Tri- Mediators Inflamm 2015 143074-737
  • [3] Kothari P(2017)-acetylresveratrol attenuates lipopolysaccharide-induced acute respiratory distress syndrome via MAPK/SIRT1 pathway Am J Respir Cell Mol Biol 56 727-144
  • [4] Young JL(2015)Fibroblast growth factor signaling mediates pulmonary endothelial glycocalyx reconstitution J Mol Cell Cardiol 88 133-515
  • [5] Dean DA(2016)Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice PLoS ONE 11 e0167576-6
  • [6] Ma L(2015)Glycocalyx degradation induces a proinflammatory phenotype and increased leukocyte adhesion in cultured endothelial cells under flow J Leukoc Biol 98 503-186
  • [7] Zhao Y(2018)Role of the endothelial surface layer in neutrophil recruitment Thromb Res 171 1-3211
  • [8] Wang R(2013)Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis Tissue Barriers 1 23494-26
  • [9] Chen T(2017)The endothelial glycocalyx: an important regulator of the pulmonary vascular barrier PLoS Pathog 13 e1006673-85
  • [10] Li W(2019)Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components Microcirculation 31 e12534-2110