Research progress of response strategies based on tumor microenvironment in drug delivery systems

被引:0
作者
Xiu’e Li
Xiaotong Yang
Rongxia Wu
Naijun Dong
Xiumei Lu
Peng Zhang
机构
[1] Shenyang Pharmaceutical University,
来源
Journal of Nanoparticle Research | 2021年 / 23卷
关键词
Nanocarrier; Tumor microenvironment; Stimuli-responsive; Drug delivery;
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学科分类号
摘要
In recent years, nanomedicines have shown tremendous progress in their targeted delivery systems and effective anticancer functions. The targeting, solubility, chemical stability, and degradability of nanocarriers make them widely used. The tumor microenvironment is different from that of normal cells. According to the response characteristics of pH, reducibility, hypoxia, reactive oxygen species, and enzymes, a series of tumor microenvironment stimulation–responsive nanocarrier delivery platforms were constructed.
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