Highly active RRMS and ocrelizumab after failure of alemtuzumab therapy

被引:0
作者
Martin Vališ
Pavel Ryška
Simona Halúsková
Blanka Klímová
Zbyšek Pavelek
机构
[1] Faculty of Medicine and University Hospital Hradec Králové,Department of Neurology
[2] Charles University in Prague,Department of Radiology
[3] University Hospital Hradec Králové,undefined
来源
BMC Neurology | / 20卷
关键词
Multiple sclerosis; Case report; Relapse; Disease progression; Alemtuzumab; Treatment failure; Lymphocytes; Ocrelizumab;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 47 条
[1]  
Miller JR(2004)The importance of early diagnosis of multiple sclerosis J Manag Care Pharm 10 S4-S11
[2]  
Baker D(2017)Interpreting lymphocyte reconstitution data from the pivotal phase 3 trials of alemtuzumab JAMA Neurol 74 961-969
[3]  
Herrod SS(2017)Memory B cells are major targets for effective immunotherapy in relapsing multiple sclerosis EBioMedicine. 16 41-50
[4]  
Alvarez-Gonzalez C(2020)Event-driven immunoprofiling predicts return of disease activity in alemtuzumab-treated multiple sclerosis Front Immunol 11 56-293
[5]  
Giovannoni G(2015)Monoclonal antibody therapies for the treatment of relapsing-remitting multiple sclerosis: differentiating mechanisms and clinical outcomes Ther Adv Neurol Disord 8 274-33
[6]  
Schmierer K(2013)Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties MAbs. 5 22-91
[7]  
Baker D(2017)Lack of CD4+ T cell percent decrease in alemtuzumab-treated multiple sclerosis patients with persistent relapses J Neuroimmunol 313 89-61
[8]  
Marta M(2013)Clinical relevance of differential lymphocyte recovery after alemtuzumab therapy for multiple sclerosis Neurology. 80 55-2164
[9]  
Pryce G(2014)Accelerated lymphocyte recovery after alemtuzumab does not predict multiple sclerosis activity Neurology. 82 2158-undefined
[10]  
Giovannoni G(2019)Lymphocyte pharmacodynamics are not associated with autoimmunity or efficacy after alemtuzumab Neurol Neuroimmunol Neuroinflamm 7 undefined-undefined