New Aureothin Derivative, Alloaureothin, from Streptomyces sp. MM23

被引：0
作者：
Jun-ya Ueda
Junko Hashimoto
Aya Nagai
Takuji Nakashima
Hisayuki Komaki
Kozue Anzai
Shigeaki Harayama
Takayuki Doi
Takashi Takahashi
Kazuo Nagasawa
Tohru Natsume
Motoki Takagi
Kazuo Shin-ya
机构：
[1] Biological Information Research Center (BIRC),Department of Biotechnology and Life Science
[2] National Institute of Advanced Industrial Science and Technology (AIST),undefined
[3] Japan Biological Information Research Center (JBIRC),undefined
[4] Japan Biological Informatics Consortium (JBIC),undefined
[5] NITE Biological Resource Center (NBRC),undefined
[6] National Institute of Technology and Evaluation (NITE),undefined
[7] Graduate School of Science and Engineering,undefined
[8] Tokyo Institute of Technology,undefined
[9] Tokyo University of Agriculture and Technology,undefined
来源：
The Journal of Antibiotics | 2007年 / 60卷
关键词：
polypropionate; alloaureothin; sp.; cytotoxic;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new polypropionate alloaureothin (1) possessing a nitro group, together with a known polypropionate aureothin (2), was isolated from mycelium of Streptomyces sp. MM23. The structure was determined on the basis of spectroscopic data. 1 exhibited growth inhibitory effect against human fibrosarcoma HT1080 cells with an IC50 value of 30 μM.
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页码：321 / 324
页数：3
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