PPARγ activation serves as therapeutic strategy against bladder cancer via inhibiting PI3K-Akt signaling pathway

被引:0
作者
Shidong Lv
Wei Wang
Hongyi Wang
Yongtong Zhu
Chengyong Lei
机构
[1] Nanfang Hospital,Department of Urology
[2] Southern Medical University,Department of Pathology
[3] General Hospital of Southern Theater Command,Department of Obstetrics and Gynecology, Center for Reproductive Medicine
[4] PLA,undefined
[5] Nanfang Hospital,undefined
[6] Southern Medical University,undefined
来源
BMC Cancer | / 19卷
关键词
Bladder cancer; PPARγ; PI3K; Akt; Apoptosis;
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[1]  
Collaborators GDIIP(2016)Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the global burden of disease study 2015 Lancet. 388 1545-1602
[2]  
Chavan S(2014)International variations in bladder cancer incidence and mortality Eur Urol 66 59-73
[3]  
Bray F(2014)Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer Nat Rev Urol 11 400-410
[4]  
Lortet-Tieulent J(2014)Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and basal subtypes Cell Rep 9 1235-1245
[5]  
Goodman M(2014)Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507 315-322
[6]  
Jemal A(2017)Oncogenic characterization and pharmacologic sensitivity of activating fibroblast growth factor receptor (FGFR) genetic alterations to the selective FGFR inhibitor Erdafitinib Mol Cancer Ther 16 1717-1726
[7]  
Choi W(2017)Comprehensive molecular characterization of muscle-invasive bladder Cancer Cell. 171 540-556 e525
[8]  
Czerniak B(2014)Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy Cancer Cell 25 152-165
[9]  
Ochoa A(2016)FOXA1, GATA3 and PPAR cooperate to drive luminal subtype in bladder Cancer: a molecular analysis of established human cell lines Sci Rep 6 1109.e1101-1109.e1106
[10]  
Su X(2013)Higher expression of peroxisome proliferator-activated receptor gamma or its activation by agonist thiazolidinedione-rosiglitazone promotes bladder cancer cell migration and invasion Urology. 81 6987-6998