Structure of transcribing mammalian RNA polymerase II

被引:0
|
作者
Carrie Bernecky
Franz Herzog
Wolfgang Baumeister
Jürgen M. Plitzko
Patrick Cramer
机构
[1] Max Planck Institute for Biophysical Chemistry,Department of Molecular Biology
[2] Gene Center Munich,Department of Molecular Structural Biology
[3] Ludwig-Maximilians-Universität München,undefined
[4] Max Planck Institute for Biochemistry,undefined
来源
Nature | 2016年 / 529卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The first high-resolution, cryo-electron microscopy structure of mammalian RNA polymerase II, in the form of a transcribing complex comprising DNA template and RNA transcript.
引用
收藏
页码:551 / 554
页数:3
相关论文
共 50 条
  • [41] A mammalian SRB protein associated with an RNA polymerase II holoenzyme
    Chao, DM
    Gadbois, EL
    Murray, PJ
    Anderson, SF
    Sonu, MS
    Parvin, JD
    Young, RA
    NATURE, 1996, 380 (6569) : 82 - 85
  • [42] Different populations of RNA polymerase II in living mammalian cells
    Miki Hieda
    Henry Winstanley
    Philip Maini
    Francisco J. Iborra
    Peter R. Cook
    Chromosome Research, 2005, 13 : 135 - 144
  • [43] DNA-directed termination of mammalian RNA polymerase II
    Davidson, Lee
    Rouviere, Jerome O.
    Sousa-Luis, Rui
    Nojima, Takayuki
    Proudfoot, Nicholas J.
    Jensen, Torben Heick
    West, Steven
    GENES & DEVELOPMENT, 2024, 38 (21-24) : 998 - 1019
  • [44] Structure of an RNA polymerase II preinitiation complex
    Murakami, Kenji
    Tsai, Kuang-Lei
    Kalisman, Nir
    Bushnell, David A.
    Asturias, Francisco J.
    Kornberg, Roger D.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (44) : 13543 - 13548
  • [45] Structure of an inactive RNA polymerase II dimer
    Aibara, Shintaro
    Dienemann, Christian
    Cramer, Patrick
    NUCLEIC ACIDS RESEARCH, 2021, 49 (18) : 10747 - 10755
  • [46] RNA polymerase II transcription: Structure and mechanism
    Liu, Xin
    Bushnell, David A.
    Kornberg, Roger D.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2013, 1829 (01): : 2 - 8
  • [47] Effect of thymine glycol on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II
    Tornaletti, S
    Maeda, LS
    Lloyd, DR
    Reines, D
    Hanawalt, PC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (48) : 45367 - 45371
  • [48] Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II
    Cline, SD
    Riggins, JN
    Tornaletti, S
    Marnett, LJ
    Hanawalt, PC
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (19) : 7275 - 7280
  • [49] Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2
    Fianu, Isaac
    Dienemann, Christian
    Aibara, Shintaro
    Schilbach, Sandra
    Cramer, Patrick
    COMMUNICATIONS BIOLOGY, 2021, 4 (01)
  • [50] Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2
    Isaac Fianu
    Christian Dienemann
    Shintaro Aibara
    Sandra Schilbach
    Patrick Cramer
    Communications Biology, 4