Clinical and genetic factors associated with increased risk of severe liver toxicity in a monocentric cohort of HIV positive patients receiving nevirapine-based antiretroviral therapy

被引:0
作者
Andrea Giacomelli
Agostino Riva
Felicia Stefania Falvella
Maria Letizia Oreni
Dario Cattaneo
Stefania Cheli
Giulia Renisi
Valentina Di Cristo
Angelica Lupo
Emilio Clementi
Stefano Rusconi
Massimo Galli
Anna Lisa Ridolfo
机构
[1] DIBIC Luigi Sacco - University of Milan,Infectious Diseases Unit
[2] ASST Fatebenefratelli-Sacco,undefined
[3] Clinical Pharmacology Unit,undefined
[4] E. Medea Scientific Institute,undefined
来源
BMC Infectious Diseases | / 18卷
关键词
Nevirapine; Pharmacogenetic; Hepatotoxicity; ABCB1;
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[1]  
Milinkovic A(2004)Nevirapine in the treatment of HIV Expert Rev Anti-Infect Ther 2 367-373
[2]  
Martínez E(2016)Dat’AIDS study group. Long-term efficacy and toxicity of abacavir/lamivudine/nevirapine compared to the most prescribed ARV regimens before 2013 in a French Nationwide cohort study Medicine (Baltimore) 95 110-117
[3]  
De Boissieu P(2010)Twelve-year experience of nevirapine use: benefits and convenience for long-term management in a French cohort of HIV-1-infected patients HIV Clin Trials 11 120-125
[4]  
Dramé M(2015)Effectiveness of a treatment switch to Nevirapine plus Tenofovir and Emtricitabine (or lamivudine) in adults with HIV-1 suppressed viremia PLoS One 10 S21-S33
[5]  
Raffi F(2004)Serious adverse cutaneous and hepatic toxicities associated with nevirapine use by non-HIV-infected individuals J Acquir Immune Defic Syndr 35 S80-S89
[6]  
Reliquet V(2003)A comprehensive hepatic safety analysis of nevirapine in different populations of HIV infected patients J Acquir Immune Defic Syndr 34 1689-1699
[7]  
Allavena C(2004)Drug-induced liver injury associated with the use of nonnucleoside reverse-transcriptase inhibitors Clin Infect Dis 38 325-333
[8]  
Morineau-Le Houssine P(2017)Multicenter study of skin rashes and hepatotoxicity in antiretroviral-naïve HIV-positive patients receiving non-nucleoside reverse-transcriptase inhibitor plus nucleoside reverse-transcriptase inhibitors in Taiwan PLoS One 12 448-452
[9]  
Mounoury O(2009)Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy AIDS 23 825-829
[10]  
Raffi F(2007)EuroSIDA study group. Risk of discontinuation of nevirapine due to toxicities in antiretroviral-naïve and -experienced HIV-infected patients with high and low CD4+ T-cell counts Antivir Ther 12 895-901