Changes to the identity of EndoC-βH1 beta cells may be mediated by stress-induced depletion of HNRNPD

[1] Cnop M(2008)Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes Biochem Soc Trans 36 348-352

[2] Butler AE(2003)Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes Diabetes 52 102-110

[3] Remedi MS(2016)Pancreatic beta-cell identity in diabetes Diabetes Obes Metab 18 110-116

[4] Emfinger C(2015)Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors Diabetes Care 38 323-328

[5] Oram RA(2016)Single-cell transcriptome profiling of human pancreatic islets in health and type 2 diabetes Cell Metab 24 593-607

[6] Segerstolpe A(2016)A single-cell transcriptome atlas of the human pancreas Cell Syst 3 385-394.e383

[7] Muraro MJ(2020)Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity Diabetologia 63 1990-1998

[8] Rutter GA(2012)Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure Cell 150 1223-1234

[9] Georgiadou E(2014)Pdx1 maintains β cell identity and function by repressing an α cell program Cell Metab 19 259-271

[10] Martinez-Sanchez A(2007)Islet alpha-cells do not influence insulin secretion from beta-cells through cell-cell contact Endocrine 31 61-65

[1] Cnop M(2008)Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes Biochem Soc Trans 36 348-352

[2] Butler AE(2003)Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes Diabetes 52 102-110

[3] Remedi MS(2016)Pancreatic beta-cell identity in diabetes Diabetes Obes Metab 18 110-116

[4] Emfinger C(2015)Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors Diabetes Care 38 323-328

[5] Oram RA(2016)Single-cell transcriptome profiling of human pancreatic islets in health and type 2 diabetes Cell Metab 24 593-607

[6] Segerstolpe A(2016)A single-cell transcriptome atlas of the human pancreas Cell Syst 3 385-394.e383

[7] Muraro MJ(2020)Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity Diabetologia 63 1990-1998

[8] Rutter GA(2012)Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure Cell 150 1223-1234

[9] Georgiadou E(2014)Pdx1 maintains β cell identity and function by repressing an α cell program Cell Metab 19 259-271

[10] Martinez-Sanchez A(2007)Islet alpha-cells do not influence insulin secretion from beta-cells through cell-cell contact Endocrine 31 61-65