Epigenetic remodelling in human hepatocellular carcinoma

被引：0
作者：
Maria Rita Braghini
Oriana Lo Re
Ilaria Romito
Maite G. Fernandez-Barrena
Barbara Barbaro
Silvia Pomella
Rossella Rota
Manlio Vinciguerra
Matias A. Avila
Anna Alisi
机构：
[1] Bambino Gesù Children’s Hospital,Unit of Molecular Genetics of Complex Phenotypes
[2] IRCCS,Department of Translational Stem Cell Biology
[3] Research Institute of the Medical University of Varna,Hepatology Program, CIMA
[4] University of Navarra,Department of Paediatric Haematology/Oncology and Cellular and Gene Therapy
[5] Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd),undefined
[6] Carlos III National Institute of Health,undefined
[7] Bambino Gesù Children’s Hospital,undefined
[8] IRCCS,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 41卷
关键词：
HCC; Epigenetics; Methylation; Non-coding RNAs; Histone modifications; Epidrugs;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, being the sixth most commonly diagnosed cancer and the fourth leading cause of cancer-related death. As other heterogeneous solid tumours, HCC results from a unique synergistic combination of genetic alterations mixed with epigenetic modifications.
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