Eicosapentaenoic acid potentiates the therapeutic effects of adipose tissue-derived mesenchymal stromal cells on lung and distal organ injury in experimental sepsis

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作者
Johnatas D. Silva
Miquéias Lopes-Pacheco
Ligia L. de Castro
Jamil Z. Kitoko
Stefano A. Trivelin
Natália R. Amorim
Vera L. Capelozzi
Marcelo M. Morales
Bianca Gutfilen
Sergio A. L. de Souza
Daniel J. Weiss
Bruno L. Diaz
Patricia R. M. Rocco
机构
[1] Universidade Federal do Rio de Janeiro,Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Centro de Ciências da Saúde
[2] Federal University of Rio de Janeiro,Laboratory of Inflammation, Carlos Chagas Filho Biophysics Institute
[3] University of São Paulo,Department of Pathology, School of Medicine
[4] Federal University of Rio de Janeiro,Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Biophysics Institute
[5] National Institute of Science and Technology for Regenerative Medicine,Department of Radiology, School of Medicine
[6] Federal University of Rio de Janeiro,Department of Medicine, College of Medicine
[7] University of Vermont,undefined
来源
Stem Cell Research & Therapy | / 10卷
关键词
Sepsis; Mesenchymal stromal cells; Preconditioning; Eicosapentaenoic acid; Inflammation; Macrophages;
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  • [1] Gotts JE(2016)Sepsis: pathophysiology and clinical management BMJ. 353 i1585-588
  • [2] Matthay MA(2015)Pharmacological treatments for acute respiratory distress syndrome: systematic review Minerva Anestesiol 81 567-1286
  • [3] Duggal A(2014)Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema Respir Res 15 118-e140
  • [4] Ganapathy A(2017)Mesenchymal stromal cells modulate macrophages in clinically relevant lung injury models by extracellular vesicles mitochondrial transfer Am J Respir Crit Care Med 196 1275-312
  • [5] Ratnapalan M(2018)Mesenchymal stem cells from bone marrow, adipose tissue, and lung tissue differentially mitigate lung and distal organ damage in experimental acute respiratory distress syndrome Crit Care Med 46 e132-L1013
  • [6] Adhikari NK(2019)Serum from asthmatic mice potentiates the therapeutic effects of mesenchymal stromal cells in experimental allergic asthma Stem Cells Transl Med 8 301-32
  • [7] Antunes MA(2012)Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes Am J Physiol Lung Cell Mol Physiol. 302 L1003-1057
  • [8] Abreu SC(2015)Combination therapy of menstrual derived mesenchymal stem cells and antibiotics ameliorates survival in sepsis Stem Cell Res Ther 6 199-635
  • [9] Cruz F(2014)Additional benefit of combined therapy with melatonin and apoptotic adipose-derived mesenchymal stem cell against sepsis-induced kidney injury J Pineal Res 57 16-32
  • [10] Teixeira AC(2016)Treatment with human Wharton’s jelly-derived mesenchymal stem cells attenuated sepsis-induced kidney injury, liver, injury and endothelial dysfunction Stem Cell Trans Med 5 1048-162