Investigation of androgen receptor CAG repeats length in polycystic ovary syndrome diagnosed using the new international evidence-based guideline

被引：0

作者：

Xueqi Yan

Xueying Gao

Qian Shang

Ziyi Yang

Yuteng Wang

Li Liu

Wei Liu

Dan Liu

Fang Cheng

Shigang Zhao

Han Zhao

Junli Zhao

Zi-Jiang Chen

机构：

[1] Shandong University,Center for Reproductive Medicine

[2] State Key Laboratory of Reproductive Medicine and Offspring Health,Key Laboratory of Reproductive Endocrinology of Ministry of Education

[3] Shandong University,National Research Center for Assisted Reproductive Technology and Reproductive Genetics

[4] Shandong Key Laboratory of Reproductive Medicine,Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine

[5] Shandong Provincial Clinical Research Center for Reproductive Health,Department of Obstetrics and Gynecology, Reproductive Medicine Center

[6] Shandong Technology Innovation Center for Reproductive Health,Department of Reproductive Medicine

[7] Shandong University,undefined

[8] Shanghai Jiao Tong University,undefined

[9] Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics,undefined

[10] Yinchuan Maternal and Child Health Hospital,undefined

[11] Northwest Women’s and Children’s Hospital,undefined

[12] Tang Du Hospital,undefined

[13] The Air Force Military Medical University,undefined

[14] General Hospital of Ningxia Medical University,undefined

[15] General Hospital of Ningxia Medical University,undefined

来源：

Journal of Ovarian Research | / 16卷

关键词：

Polycystic ovary syndrome; Polycystic ovarian morphology; Androgen receptor; CAG repeats; Genetic polymorphism;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 126 条

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[2] Li Q(2022)Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification Endocr Rev 43 927-221
[3] Zhou Z(2020)Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity Clin Chim Acta 502 214-680
[4] Qian W(2022)Polycystic ovary syndrome Lancet Diabetes Endocrinol 10 668-65
[5] Zhang J(2016)Genetic studies on polycystic ovary syndrome Best Pract Res Clin Obstet Gynaecol 37 56-267
[6] Wu Z(2019)Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants Sci China Life Sci 62 257-3186
[7] Dapas M(1994)The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function Nucleic Acids Res 22 3181-188
[8] Dunaif A(1993)Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy Nat Genet 5 184-165
[9] Zeng X(2002)The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome J Clin Endocrinol Metab 87 161-2323
[10] Xie Y-J(2008)Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome Fertil Steril 90 2318-1945