Viruses, dendritic cells and the lung

被引：0
作者：
R Stokes Peebles
Barney S Graham
机构：
[1] Vanderbilt University School of Medicine,Department of Medicine
[2] National Institutes of Health,Vaccine Research Center
来源：
Respiratory Research | / 2卷
关键词：
dendritic cell; inflammation; lung; virus;
D O I：
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学科分类号：
摘要：
The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as viruses, but viruses have developed survival tactics to either evade or diminish the immune system that functions to kill and eliminate these micro-organisms. In the present review we summarize current concepts regarding the function of DCs in the immune system, our understanding of how viruses alter DC function to attenuate both the virus-specific and global immune response, and how we may be able to exploit DC function to prevent or treat viral infections.
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