Late-onset multiple sclerosis mimicking brain tumor: A case report

被引：0

作者：

Iwamoto K. ^{[1
]}

Oka H. ^{[1
]}

Utsuki S. ^{[1
]}

Ozawa T. ^{[1
]}

Fujii K. ^{[1
]}

机构：

[1] Department of Neurosurgery, Kitasato Univ. School of Medicine, Sagamihara, Kanagawa 228-8555

来源：

Brain Tumor Pathology | 2004年 / 21卷 / 2期

关键词：

Late-onset; MRI; Multiple sclerosis; Pathology; Tumorlike lesion;

D O I：

10.1007/BF02484515

中图分类号：

学科分类号：

摘要：

Multiple sclerosis (MS) is a demyelinating disease that predominantly affects those aged in their twenties to their forties. We recently observed a case of rapidly progressive late-onset MS in an elderly patient with a large, single lesion on magnetic resonance imaging (MRI), which was difficult to distinguish from a brain tumor. This case is reported here with a review of the literature. A 69-year-old woman who presented with left hemiparesis was admitted to our institute. A tumor lesion was strongly suspected from the MRI finding of a large solitary lesion adjacent to the right lateral ventricle. Her left hemiparesis became rapidly worse, so we decided to perform stereotactic biopsy. Histopathological examination indicated that the patient had a demyelinating disease such as multiple sclerosis. Steroid pulse therapy was started after the operation and led to a marked improvement of the symptoms. With follow-up for more than 1 year after discharge, she has shown no sign of relapse. Late-onset MS should be suspected if edema or mass effect is not visualized around the lesion on MRI, bearing in mind that late-onset MS can have a progressive course in elderly patients.

引用

页码：83 / 86

页数：3

共 22 条

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