Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice

被引:0
作者
Hui Yu
Shumin Shao
Junnan Xu
Haibiao Guo
Zhangfeng Zhong
Jiangping Xu
机构
[1] Southern Medical University,Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences
[2] University of Macau,Macau Centre for Research and Development in Chinese Medicine, Institute of Chinese Medical Sciences
[3] Southern Medical University,Department of Neurobiology, School of Basic Medical Sciences
[4] Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co.,undefined
[5] Ltd,undefined
来源
Chinese Medicine | / 17卷
关键词
Persimmon leaf; Depression; Serotonin reuptake; Dendritic spines; cAMP/CREB/BDNF signaling pathway; Microbiota–gut–brain axis;
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  • [1] Howard DM(2019)Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions Nat Neurosci 2 343-52
  • [2] Adams MJ(2020)Effect of long-term vitamin D3 supplementation vs placebo on risk of depression or clinically relevant depressive symptoms and on change in mood scores: a randomized clinical trial JAMA 324 471-80
  • [3] Clarke TK(2012)Melatonin and its analogs in insomnia and depression J Pineal Res 52 365-75
  • [4] Hafferty JD(2010)Collaborative care for patients with depression and chronic illnesses N Engl J Med 363 2611-20
  • [5] Gibson J(2017)Cellular and molecular basis for stress-induced depression Mol Psychiatry 22 1440-47
  • [6] Shirali M(2015)Research on the pathological mechanism and drug treatment mechanism of depression Curr Neuropharmacol 13 514-23
  • [7] Okereke OI(2019)Depression in the primary care setting N Engl J Med 380 559-68
  • [8] Reynolds CR(2019)Deciphering the metabolic role of AMPK in cancer multi-drug resistance Semin Cancer Biol 56 56-71
  • [9] Mischoulon D(2021)Psychotic depression: diagnosis, differential diagnosis, and treatment Psychother Psychosom 90 160-77
  • [10] Chang G(2019)Targeting Serotonin1A receptors for treating chronic pain and depression Curr Neuropharmacol 17 1098-108