Pancreatic insufficiency in patients with chronic graft-versus-host disease

被引：0
作者：
G Akpek
JL Valladares
L Lee
J Margolis
GB Vogelsang
机构：
[1] Hematologic Malignancies,Department of Oncology
[2] The Johns Hopkins University School of Medicine,Department of Medicine
[3] Gastroenterology,undefined
[4] The Johns Hopkins University School of Medicine,undefined
来源：
Bone Marrow Transplantation | 2001年 / 27卷
关键词：
chronic GVHD; malabsorption; diarrhea; pancreas; pancreatic insufficiency;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition. Bone Marrow Transplantation (2001) 27, 163–166.
引用
收藏
页码：163 / 166
页数：3
相关论文
共 47 条
[1]  
Spencer GD(1986)Diffuse intestinal ulceration after marrow transplantation. A clinical–pathological study of 13 patients Hum Pathol 17 621-633
[2]  
Shulman HM(1986)Intestinal and hepatic complications of human bone marrow transplantation Gastroenterology 90 460-477
[3]  
Myerson D(1991)Graft vs host disease New Engl J Med 324 667-674
[4]  
McDonald GB(1990)Graft-versus-host disease of the gastrointestinal tract Am J Surg Pathol 14 101-108
[5]  
Shulman HM(1994)Graft versus host disease: new directions for a persistent problem Blood 84 2061-2067
[6]  
Sullivan HM(1985)A histopathologic study of gastric and small intestinal GVHD following allogeneic BMT Hum Pathol 16 387-392
[7]  
Ferrara JLM(1991)Pancreatic insufficiency after bone marrow transplantation (letter) Lancet 11 517-1086
[8]  
Degg HJ(1991)Pancreatic insufficiency after bone-marrow transplantation Lancet 11 1089 (letter)-664
[9]  
Snover DC(1991)Pancreatic insufficiency after bone-marrow transplantation Lancet 11 1088 (letter)-77
[10]  
Vogelsang G(1997)Acute pancreatitis in marrow transplantation patients: prevalence at autopsy and risk factor analysis Bone Marrow Transplant 20 1081-448
12345