Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls

被引：0
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作者：
Alexandra R. Buckley
Kristopher A. Standish
Kunal Bhutani
Trey Ideker
Roger S. Lasken
Hannah Carter
Olivier Harismendy
Nicholas J. Schork
机构：
[1] University of California,Biomedical Sciences Graduate Program
[2] J. Craig Venter Institute,Bioinformatics and Systems Biology Sciences Graduate Program
[3] University of California,Division of Medical Genetics, Department of Medicine
[4] University of California San Diego,Moores Cancer Center
[5] University of California San Diego,Cancer Cell Map Initiative (CCMI)
[6] University of California San Diego,Microbial Genomics Program
[7] J. Craig Venter Institute,Division of Biomedical Informatics, Department of Medicine
[8] University of California San Diego,undefined
[9] The Translational Genomics Research Institute,undefined
来源：
BMC Genomics | / 18卷
关键词：
Cancer genomics; TCGA; Cancer germline; Whole exome sequencing; Variant calling; GATK; Batch effects; Whole genome amplification; Variant annotation; Genetic association testing;
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