Laryngeal leiomyosarcoma: a case report and review of the literature

被引:0
作者
Charalambos E. Skoulakis
Pelagia Stavroulaki
Panagiotis Moschotzopoulos
Mihalis Paxinos
Angela Fericean
Dimitris E. Valagiannis
机构
[1] “Achillopoulion” General Hospital of Volos,ENT Department
[2] “Achillopoulion” General Hospital of Volos,Department of Pathology
来源
European Archives of Oto-Rhino-Laryngology and Head & Neck | 2006年 / 263卷
关键词
Larynx; Leiomyosarcoma; Emergency tracheotomy; Laryngeal cancer;
D O I
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学科分类号
摘要
Laryngeal leiomyosarcoma (LLM) is a rare malignancy originating from the smooth muscles of blood vessels or from aberrant undifferentiated mesenchymal tissue. Histological diagnosis may be particularly difficult and correct diagnosis is based on immunohistochemical investigations and electron microscopy. A case report of a LLM in a 74-year-old man is presented. Direct laryngoscopy revealed a large glottic lesion causing airway compromise and an emergency tracheotomy was performed. Subsequent total laryngectomy confirmed the diagnosis of leiomyosarcoma. Lung metastases developed 8 months following treatment, despite the absence of local or regional recurrence, and the patient died 3 months later. A review of the English and French literature revealed 30 previous cases of LLM. Clinical presentation, histological diagnosis, and management of this rare malignancy are analyzed aiming to improve our knowledge regarding the best treatment modality.
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页码:929 / 934
页数:5
相关论文
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